The central retinal thickness was significantly higher in the preterm groups than in the full-term group. This subtle macular modification may be related mainly to ROP. Prematurity had only a marginally significant role.

ABSTRACT.Purpose: This study aimed to compare preoperatively calculated and postoperatively achieved refraction following phacoemulsification and intraocular lens (IOL) implantation combined with pars plana vitrectomy with internal limiting membrane or epiretinal membrane removal. Methods: Twelve eyes of 12 patients who underwent a combined procedure were enrolled in this study. Ultrasound axial length and macular thickness (optical coherence tomography, OCT) measurements were performed pre-and postoperatively. Intraocular lens power was calculated with the SRK ⁄ T formula and the planned refraction was compared with results of postoperative automatic refractometry. Comparisons between IOL calculations using the measured axial length and calculations using an adjusted axial length (by adding the macular thickness measured on OCT to the ultrasound axial length) were also performed. Results: Axial length increased (p ¼ 0.02), whereas macular thickness decreased (p ¼ 0.002). The planned refraction was 0.63 ± 0.38 dioptres, whereas the postoperative refraction error was ) 0.16 ± 0.48 D (p ¼ 0.02), with a mean difference of ) 0.79 ± 0.24 D. During case-to-case comparisons, differences were observed between IOL calculations using the measured axial length and calculations using an adjusted axial length (0.63 ± 0.38 D versus 0.13 ± 0.48 D, p ¼ 0.005). Correlation analysis showed a significant relationship between the 'adjusted planned' and the measured postoperative ametropia (r ¼ 0.93, p < 0.001). Conclusions: The observed myopic shift due to erroneous IOL calculation results from underestimation of the axial length due to a thicker macula and calls for preoperative adjustment of ultrasound axial length when biometry is performed by this method.

Patients with chronic central serous chorioretinopathy can safely be treated with eplerenone as it can reverse choroidal vasodilation with an accompanying resolution of the SRF and improvement in visual acuity. These beneficial therapeutic effects are more pronounced in the exudative eyes.

Diabetes mellitus itself and the severity of DR affect CT significantly, even after adjusting for the effects of confounding systemic factors. Disease duration seems to be associated with a reduction of choroidal thickness. Decreased CT proved to be correlated with the severity of DR.

BackgroundThis study aimed to determine the relationship between image quality and measurement repeatability of optical coherence tomography angiography (OCTA) parameters in patients with non-proliferative diabetic retinopathy.MethodsA total of 100 eyes of 50 patients were included in the study. Three OCTA images were obtained consecutively during one session of imaging in all patients using the RTVue AngioVue OCTA device. We applied the signal strength index (SSI) provided by the RTVue system to define scan quality. Superficial vessel density (VD) in the central 3 × 3 mm macular and in the perifoveal region, as well as foveal avascular zone (FAZ) area were evaluated by the AngioAnalytics software for each scan from three consecutive measurements, whereby measurement repeatability of the OCTA parameters were calculated. The effect of SSI value on OCTA parameters, as well as on measurement errors was assessed.ResultsValues of SSI ranged from 30 to 85 with an overall mean of 61.79 ± 10.38. Mean SSI values showed significant positive correlation with the mean retinal capillary vessel density values, but not with non-flow area. Repeatability of OCTA parameters was generally improved with higher SSI values. We calculated a mean correction factor of 0.22% (95% CI 0.20–0.24 µm; p < 0.001) for VD at the 3 × 3 mm macular scan, 0.23% (95% CI 0.21–0.26%; p < 0.001) for perifoveal VD and − 0.001 mm2 (95% CI − 0.001 to 0.002; p = 0.001) for the non-flow area for each unit increase in SSI for the comparison of images with different SSI values.ConclusionsThe influence of image quality on OCTA metrics should be considered for image comparisons during follow-up to avoid misinterpretation of small changes in OCTA parameters in patients with diabetes.