Цель. Оценить влияние избыточного веса на связанное со здоровьем качество жизни (СЗКЖ) подростков (физическое функционирование (ФФ), эмоциональное функционирование (ЭФ), социальное функционирование (СФ), школьное функционирование (ШФ), психосоциальное функционирование (ПCФ)), проживающих в сельских районах Республики Бурятия. Материалы и методы. Обследовано 77 подростков с избыточным весом и ожирением, проживающих в сельских районах Бурятии (46 монголоидов и 31 европеоид) и 73 сопоставимых с ними по полу, возрасту и расово-этническому составу подростка с нормальным весом. Были измерены рост, вес, окружность талии, вычислен индекс массы тела. СЗКЖ оценено с применением русской версии опросника PedsQL™ 4.0. Результаты. У подростков-европеоидов с избыточным весом баллы СЗКЖ общего и во всех доменах оказались значительно ниже, чем у подростков с нормальным весом (все p < 0,01). Баллы СЗКЖ в подгруппах сойотов и бурят с избыточным весом не имели значимых различий и были сопоставимы с баллами группы контроля. Регрессионный анализ, выполненный с учетом пола, возраста, стадии полового созревания подростков, образования и социального статуса их матерей, показал, что принадлежность к европеоидам является независимым предиктором худшего СЗКЖ как общего, так и во всех его доменах (β =-0,42; р = 0,0001 для общего КЖ; β =-0,48; р = 0,0001 для ФФ; β =-0,32; р = 0,004 для ЭФ; β =-0,41; р = 0,0001 для СФ; β =-0,3; р = 0,007 для ШФ; β =-0,39; р = 0,001 для ПСФ). Кроме того, независимо от этнической принадлежности абдоминальный характер ожирения был связан с худшим СЗКЖ в доменах эмоционального (β =-0,26; р = 0,018), школьного (β =-0,23; р = 0,03), психосоциального (β =-0,24; р = 0,028) функционирования, а также баллами общего качества жизни (β =-0,22; р = 0,04). Заключение. Худшее качество жизни у сельских подростков с избыточным весом и ожирением в Бурятии сопряжено с принадлежностью к европеоидам и абдоминальным характером жироотложения, что обосновывает необходимость разработки этноспецифических профилактических программ.
BACKGROUND: The melanocortin 4 receptor gene (MC4R) codes the receptor expressed in the hypothalamus and involved in the regulation of body mass and height. Data on the association of polymorphism MC4R rs17782313 with anthropometric parameters are contradictory. AIMS: to study the influence of the carrier of polymorphism MC4R rs17782313 on the anthropometric parameters in adolescents of different ethnic groups: caucasians and mongoloids living in the Siberia. MATERIALS AND METHODS: The study included 179 caucasian adolescents (by the example of russians, average age is 15.07 1.25 years) and 182 mongoloid adolescents (by the example of the buryats, the average age is 14.71 1.28 years), 89 and 92 adolescents were included in groups with overweight and obesity (standard deviation (SDS) BMI 1), in the control groups (SDS BMI from -1 to + 1) also 90 and 90 adolescents were included in the control groups (SDS BMI from -1 to + 1) (russian and buryat, respectively). Anthropometric measurements included height, weight with the calculation of BMI and SDS BMI, WC (waist circumference), HC (hip circumference ). Genotyping was performed by real-time PCR. Statistical analysis of the results of the study was carried out using the software STATISTICA 8.0. RESULTS: We showed no association of the risky C-allele of polymorphism rs17782313 with overweight and obesity in russian adolescents (22.5% vs 17.9% OR = 1.34 (p 0.05)) and in the buryat (29.8% vs 24.1%, OR = 1.43 (p 0.05)). It was revealed that adolescent carriers of the C-allele in buryat showed higher growth in both groups (control: 162.19 cm vs 157.26 cm (p = 0.019)), the main group: 165.24 cm vs 164.91 cm (p = 0.041)), as well as weight gain in the control group (52.29 kg vs 48.05 kg (p = 0.028)). CONCLUSIONS: Thus, the study revealed the relationship of MC4R rs17782313 polymorphism with height and weight in adolescents of buryat ethnic group.
Background: According to WHO forecasts, childhood obesity can soon become equally dangerous to public health as malnutrition and infectious diseases. Elimination of modifiable risk factors is important for the disease and disease-associated complications prevention. At the same time it is shown that the risk factors can vary widely not only from country to country but also from area to area within one country. Aim: To establish risk factors associated with obesity in adolescents in rural areas of Buryatia, Russia. Materials and methods: The cross-sectional study included 1117 year old adolescents with normal weight (BMI 2575 percentile) and obesity (BMI 95 percentile). We assessed anthropometric measures of adolescents and their parents, sociodemographic characteristics, early-life exposures, eating and lifestyle patterns. Results: The study included 128 adolescents with normal weight and 72 adolescents with obesity. Both groups were comparable by sex, age and ethnicity. Factors, associated with obesity in rural adolescents, were: parents obesity (odds ratio (OR) 3.63 (95% confidence interval (CI) 1.926.87); the mothers body mass index (OR 1.17 (95% CI 1.11.25)); duration of breast-feeding less than 4 months (OR 2.42 (95% CI 1.145.13)); disturbed dietary pattern (OR 2.54 (95% CI 1.15.88)). Factors showing protective effect were total breast-feeding duration (OR 0.94 (95% CI 0.890.99)) and mothers employment as a skilled worker (OR 0.51 (95% CI 0.270.96)). Conclusions: Characteristics of family (obesity in parents, mothers BMI), breast-feeding less than 4 months and the disturbed dietary pattern are the risk factors associated with obesity in adolescents living in rural areas of Buryatia which are worth considering when local obesity prevention programs are being developed.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.