Третья объединенная рабочая группа Европейского общества кардиологов и других Европейских обществ по профилактике сердечно-сосудистых заболеваний в клинической практике** Председатель рабочей группы G.
These data suggest that subjects with high normal BP and elevated serum cholesterol might have an exaggerated cardiovascular response to stress and have an increased risk for stable hypertension that can be detected at young age.
In subjects with borderline (BL) hypertension and in normal subjects with familial hypertension (FH), the increase in diastolic blood pressure (DBP) induced by mental arithmetic, handgrip and bicycle exercise strongly correlates with intralymphocytic sodium concentration (ILSC). In BL subjects with high or normal ILSC basal BP values are identical, but the increase in DBP during stress is significantly greater in BL subjects with high ILSC. The same phenomenon can be found in normal subjects with FH. Four hours after acute salt loading urinary Na+ is significantly higher in BL subjects with high ILSC. ILSC is a test by which one can identify BL and normal subjects with abnormal responsiveness to stimuli and who probably are fated to develop sustained hypertension.
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