The use of preparations based on secondary plant metabolites is an alternative to chemical pesti-cides, to which the vegetable bean culture is very sensitive. Аll preparations stimulate the germination and development of the root system of seedlings, which contributes to an increase in the germination and resistance of beans to Fusarium in the early stages of development. 0.01% concentration is the most op-timal for treating beans before sowing. Verbascoside exhibits a prolonged immunomodulatory effect and effectively inhibits the development of the disease throughout the growing season. Bioregulators mold-stim and linaroside work more effectively together with chemical fungicides, reducing their phytotoxicity and increasing plant stress resiastance.