One of the effective methods of early medical diagnosis is the method of wedge dehydration. It is based on the analysis of facies images. Facia is a thin film of dried human biological fluids. The presence of special structures (markers) indicates various pathologies of the organism at their earliest stages. In this article, the algorithm for detecting spherulite marker on microscopic images of human serum facies is presented. The presence of spherulites on facies is the norm. However, the atypical form of spherulite is a marker of precancerous diseases: uterine fibroids, endometrial hyperplastic processes and the mammary gland. Due to the visual analysis of the marker, its characteristic features were identified. Then algorithmic detection methods for these features were developed. The decision on the probable presence of a marker was made if there was a combination of features of this marker. As a result of the application of the developed algorithm, most images of atypical spherulites were identified.
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