The results of the assessment of the impact of risk factors on the health of workers of the mining and processing plant are presented. The necessity to take into account the high relative risk of developing diseases of the musculoskeletal system, as well as diseases of the circulatory system in the system of monitoring the detection of workers with early signs of occupational diseases.

The paper presents the results of hygienic assessment of the working environment and process factors in surface ore mining operations. It analyzes morbidity patterns and levels of occupational diseases among employees engaged in open-pit mining of ores. Occupational risks due to the impact of harmful industrial factors on employees' health are assessed based on the results of a cross-sectional epidemiological study. It has been established that the working conditions of personnel in openpit mines, who are subjected to continuous and intensive exposure to harmful occupational factors in the course of their labour activities, contribute to higher incidence rates and risks concerned with chronic somatic diseases as compared to the intermittent exposure to the same harmful occupational factors.

The hygienic assessment of working conditions of workers of the main professions engaged in management of the mechanized vehicles at mining combine is given. The index of polymorbidity of chronic diseases was established. The experience and age at which workers are diagnosed with chronic General somatic disease for the first time are determined.

Biological monitoring is used to assess the toxic effect of mercury on the human body and to identify risk groups for the development of mercury intoxication at various stages of clinical and laboratory examination of workers who have contact with mercury vapor. A comprehensive analysis of changes in the biomarkers of exposure and effect in the conditions of professional exposure to mercury on the body of workers allows us to identify groups at increased risk of developing health disorders and optimize therapeutic and preventive measures taking into account the individual characteristics of the body. Biological monitoring should be implemented at the stage of preliminary, periodic medical examinations and in-depth examination of workers in contact with mercury vapor. Correlation and regression analysis of the data obtained showed a significant positive relationship between the average concentration of mercury in the air of the working area and the average concentration of mercury in the urine of the main occupational groups of mercury production workers.

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