No abstract

No abstract

Aim - developing of the new method of diagnosis of oral manifestations of hematologic malignancies by using concentrations of immunoglobulin A and G antibodies to gliadine and transglutaminase in saliva. Materials and methods. The condition of oral mucosa and concentrations of immunoglobulin A and G antibodies to gliadine and transglutaminase were assessed in 90 patients with acute and chronic leukemia. Results. After polychemiotherapy their oral status and concentrations of immunoglobulin A and G antibodies to gliadine and transglutaminase changed significantly. Conclusion. The study will help develop effective method of diagnosis of oral manifestations of hematologic malignancies.

The article presents data from our own research on the relationship of local oral fluid immunity in patients with acute leukemia and ulcerative-necrotic lesions of the oral mucosa after chemotherapy treatment. The state of the oral mucosa is described, and the role of the immunoassay method is indicated. The principles of local treatment of this category of patients are proposed.