Data on the synthesis of thiazoles systems condensed with heterocycles are classified. The principal directions in the practical application of these substances are briefly discussed.
A convenient approach to the synthesis of the previously unknown 7H‐furo[3,2‐b]pyran‐7‐ones based on the intramolecular cyclization of carbonyl derivatives of 5‐hydroxy‐2‐methyl‐4H‐pyran‐4‐one has been elaborated. Key intermediates in the synthesis of the target 7H‐furo[3,2‐b]pyran‐7‐ones are 3‐hydroxy‐6‐methyl‐2‐(2‐oxo‐2‐arylethyl)‐4H‐pyran‐4‐ones. They are formed as a result of multicomponent condensation of 5‐hydroxy‐2‐methyl‐4H‐pyran‐4‐one with arylglyoxals and 4‐methoxyaniline.
C Acylation of Meldrum´s acid by (het)arylacetic acids in ethanol in the presence of 1,1' carbonyldiimidazole leads to ethyl 4 (het)aryl 3 oxobutanoates in high yields.
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