The paper actualizes the issues of combating drug trafficking using the Internet on the example of Ukraine. Given the significant difference in the approach to this issue among Ukrainian and foreign scientists, this allowed to carry out a multifaceted analysis. The purpose of the article is to conduct a comprehensive study (criminological and forensic) on the use of the Internet in the commission of crimes related to drug trafficking, on the example of Ukraine. Profiling was used as the main method. The novelty of this work is the extrapolation of the method of profiling cybercriminals to persons who commit illicit drug distribution using the Internet in Ukraine as a special category of cybercriminals. The specific objectives of the study are: to study the characteristics of an offender who commits crimes related to drug trafficking via the Internet using the method of profiling; study of typical investigative situations that arise when committing crimes related to drug trafficking on the Internet; development of comprehensive recommendations for combating this group of crimes, taking into account both the identity of an offender and investigative situations that most often arise in practice. Based on the study, the article conducted (using secondary data) profiling of people who distribute drugs using the Internet in Ukraine. The profiling also includes a comprehensive portrait of such a criminal, which includes both socio-demographic and psychological characteristics of this category of criminals, studied their motivation, conducted a study of the victimological aspect and features of the study of evidence in this category of crimes.

Метою дослідження стало визначення можливих кореляційних зв’язків між умістом фактора некрозу пухлини альфа (ФНО-α), інтерлейкіну-6 і показниками перекис-індукованої хемілюмінесценції (ХЛ) у хворих з опіоїдною залежністю (ОЗ) від активності коморбідного хронічного гепатиту С (ХГС). Обстежено 124 хворих з ОЗ (96 чоловіків і 28 жінок) віком від 19 до 48 років, у тому числі 87 хворих із коморбідним ХГС (69 чоловіків і 18 жінок) віком від 21 до 48 років. Установлено, що динаміка інтенсивності спонтанної, індукованої хемілюмінесценції, площі перекис-індукованої хемілюмінограми вказує на максимальну активацію процесів перекисного окислення ліпідів, збільшення вмісту прооксидантних речовин, зменшення буферної антиоксидантної ємності сироватки крові в ранньому абстинентному періоді у хворих з опіоїдною залежністю, поєднаною з помірною активністю гепатиту. При оцінці кореляції сироваткового рівня ФНО-α з показниками перекис-індукованої ХЛ нами встановлено, що помірна активність коморбідного ХГС у порівнянні з малою активністю гепатиту обумовлює більш значимий вплив цього прозапального цитокіну на інтенсивність перекисного окислення ліпідів і зсув балансу «перекисне окислення ліпідів — антиоксидантний захист» (ПОЛ — АОЗ) до активації ПОЛ у ранній (R = +0,679; P < 0,001; R =  +0,525; P < 0,0017 відповідно) і пізній абстиненції (R = +0,821; P < 0,001; R = +0,808; P < 0,001 відповідно). При помірній активності коморбідного ХГС у хворих з ОЗ інтерлейкін-6 має найбільший вплив на зростання вмісту прооксидантних речовин у сироватці крові в ранній абстиненції (R = +0,740; P < 0,001), збільшення активності ПОЛ у пізній абстиненції (R = +0,480; P < 0,005; R = +0,724; P < 0,001), вірогідний зсув балансу ПОЛ — АОЗ у бік активації ПОЛ у ранній (R = +0,759; P < 0,001) і пізній абстиненції (R = +0,801; P < 0,001).

Background. The relevance and clinical and social need for this study is determined by the fact that to date, no comprehensive therapy and prevention of suicidal behavior (SB) has been developed in patients with schizophrenia from the area of the anti-terrorist operation (ATO). Objective – to analyze the features of positive and negative syndromes by using the PANSS scale before and after complex therapy in people with schizophrenia who in the past had suicidal behavior. Materials and methods. 266 people aged 22 to 50 years were selected with a diagnosis of schizophrenia, who in the past had suicidal behavior. 136 people with suicidal behavior in schizophrenia who were treated in 2014-2016 constituted the main group (МG). The control group (CG) constituted 130 people with suicidal behavior in schizophrenia who were examined in 2006-2013. Results. In order to improve care for patients with suicidal behavior in schizophrenia who have been living in the ATO zone, we proposed an algorithm for the treatment process, which included a comprehensive and phased provision of medical and social assistance. In addition to standard care using clinical protocols, we have introduced a comprehensive approach taking into account the gender characteristics of patients with schizophrenia with suicidal behavior. Integrated author’s therapy was carried out at the inpatient and outpatient stages. Treatment measures were aimed both at the patients with schizophrenia with suicidal behavior, and at their relatives. After the treatment, we analyzed dynamics of positive, negative and psychopathological syndromes according to the PANSS, compared the results obtained before and after therapy. It was found that the main number of results that have a significant difference in МG and CG, relates to general psychopathological symptoms, which were identified as markers. Conclusions. The highlighted markers of positive, negative and psychopathological syndromes, that reduce the quality of life and lead to impaired social functioning, underwent positive changes when introducing a model of comprehensive measures to help patients with suicidal behavior in schizophrenia.

As a result of the study, specific mental and behavioral disorders due to alcohol use in ATO participants were determined taking into account the levels and style of alcohol consumption. The relationship between disorders due to alcohol consumption and the consequences of combat psychological trauma is shown. It has been established that, on the whole, the transition from the conditions of a positional war to the conditions of a peaceful life is accompanied by a decrease in alcohol consumption (by individuals independent of it), a decrease in the level of harmful consequences, an improvement in mental status and a slight improvement in the quality of life, however, there are exceptions to this rule, especially with regard to stressful disorders - the level of exposure to a stressful event remains almost unchanged. Neither the army men nor the demobilized military found any adaptive (useful) medium- and long-term effects of alcohol (the transient anxiolytic and hypnotic sedative effects of alcohol have no long-term positive results (as opposed to negative ones). Psychopathological factors that affect disorders due to alcohol consumption remain almost unchanged during the transition from combat conditions to peaceful life, the influence of only certain components changes. Therefore, measures aimed at preventing maladaptation (that is, the formation of new and exacerbation of existing mental and behavioral disorders, including drug addiction) should adhere to the principle of continuity.It is advisable that between specialists and institutions suitable for the hygiene of the military and the demobilized, as high quality communication as possible is maintained along the methodological guidelines for the provision of medical and rehabilitation assistance. A significant level of consumption of psychoactive substances among combatants may indicate an unmet demand for adaptogens (both chemical and non-chemical origin), the use of which would not lead to the negative consequences of alcohol and other surfactants. This is a challenge for modern military psychopharmacology, military psychology and military psychophysiology.

Patent in Ukraine "A method for predicting pseudoabsentative syndrome in the remission period in patients with opioid dependence" (Patent of Ukraine 67150), which includes diagnostic clinical and psychopathological integrated screening, the innovative essence of which is that in addition, according to ultrasound diagnosis, detect the liver, carry out quantification the evaluation of the risk factors of relapse, compare the obtained mathematical indicators (predictive factors - digital constants, determined by statistical methods) using the system two discriminant equations, and if the absolute quantification value of the first equation (F1) exceeds the absolute value of the second (F2) equation, they predict the development of the pseudoabsentative syndrome in the next 3 months and prescribe antiretroviral therapy.