In the present review the authors analyzed the effectiveness of treatment of intraepithelial neoplasia I-II-III of the cervix (CIN), vulva (VIN) and vagina (VaIN) using photodynamic therapy (PDT). PDT is a method based on exposure to light after preliminary introduction of a photosensitizer into the body with the formation of singlet oxygen, which has a cytotoxic effect. The results of research on the use of PDT with various photosensitizers in the complex of therapeutic measures in patients with CIN, VIN, VaIN are presented. These data on the effectiveness and safety of PDT, ease of use allow this medical technology to be attributed to one of the most promising areas in the treatment of pathological intraepithelial changes of the cervix, vulva and vagina. The presented information allows focusing the attention on the PDT method and informing doctors and researchers about the broad prospects for applying this treatment method in clinical practice.
Резюме. К группе онкогинекологических заболеваний относятся злокачественные новообразования тела мат-ки, яичников, шейки матки, вульвы и влагалища (в возникновении трех последних установлена ведущая роль ВПЧ). Среди обширной группы инфекций, передаваемых половым путем (ИППП), официальной регистрации в России подлежат сифилис, гонорея, трихомоноз, хламидиоз, урогенитальный герпес и аногенитальные бо-родавки (АБ). Возникновение АБ в 95-100% случаев обусловлено ВПЧ 6 и 11 типов. Цель работы: определение места ВПЧ-ассоциированных заболеваний (рака шейки матки и АБ) в структуре онкогинекологической пато-логии и ИППП на протяжении последних лет на территории Москвы, сравнение с ситуацией по РФ в целом.
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