Introduction. Currently, there has been an improvement in the situation of tuberculosis in the Russian Federation. Despite successful preventive and diagnostic measures of phthisiatric service, cases of the disease still occur in adolescence. Purpose of work. Clinical demonstration of a case of pulmonary tuberculosis in an adolescent with concomitant pathology. Methods. A clinical case of a 16-year-old boy with infiltrative pulmonary tuberculosis, which developed against the background of a longstanding infection with MBT, presented. The rapid development of pronounced changes in the lungs, decay and infiltration may have been provoked by adolescent age and the presence of concomitant pathology. Results. Slow clinical and radiological dynamics observed in the course of the disease, but the complex approach to treatment with the use of minimally invasive non-medicinal method of valve bronchoblockage permitted to achieve positive results. Due to their physiological peculiarities, connected with hormonal reorganization of the body, teenagers are a «risk group» for tuberculosis. Discussion and Conclusion. Tuberculosis process in this age group is characterized by a number of distinctive features which are related to certain reasons, among which are anatomical and physiological peculiarities of teenagers, changes in living conditions, transition from complete social and economic dependence on adults to relative social independence and coexisting diseases. The task of general practitioners and tuberculosis doctors is to organize the early detection of tuberculosis in adolescence and to provide correct and controlled treatment.

The variety of clinical manifestations and the absence of strictly specific features make tuberculosis and toxocariasis difficult to diagnose and treat. Doctors of various specialties are engaged in the diagnosis of toxocariasis, depending on which organ system is affected in a person and with whatsymptoms he turned to a medical institution.Purpose: to describe the case of detecting toxocariasis in a child who was treated in a tuberculosis hospital from a bacillary family contact with pronounced indicators of immunological tests and revealed changes during CT scan of the chest organs.A complex differential diagnostic path and constant medical supervision made it possible to establish a rather rare disease - toxocariasis in a child from family contact with a patient with tuberculosis.Conclusion. In the differential diagnostic series in patients withtuberculosis, the presence of parasitic diseases with a similar clinical and radiological picture cannot be excluded.

Introduction. The incidence of tuberculosis in children and adolescents is considered one of the most significant epidemiological indicators, which reflects the overall epidemic situation for tuberculosis. An urgent problem is the fact that the effectiveness of treatment of tuberculosis with MDR/XDR MBT in children and adolescents is not reflected in official statistics, and the tolerability of new anti-tuberculosis drugs in children with tuberculosis is not sufficiently studied at present. One of the drugs that can be used in the treatment of MDR-TB in children is linezolid. Objective. to evaluate the safety and efficacy of linezolid in chemotherapy regimens for drug-resistant tuberculosis in children. Results. in the structure of clinical forms of infiltrative tuberculosis — (32.0%), the primary tuberculosis complex was detected in 8 people (16.0%), TB of intra-thoracic lymph nodes also in 8 people (16.0%). MBT resistance to cycloserine and linezolid has not been reported in any patients. All patients received linezolid (100%). The development of undesirable side effects was observed in 14 people (28.0%). Linezolid caused in 3 people (6.0%) (adolescents 13 — 17 years old) undesirable adverse reactions of the type of polyneuropathy. The cessation of bacterial excretion was observed after 1 month in 100 % of cases. All children showed positive clinical dynamics and normalization of blood parameters in the period from 2 to 6 months of treatment. Positive radiological dynamics were also observed in the period from 2 to 6 months of treatment in the form of closure of the decay cavities, compaction, calcification and resorption of foci. Conclusion. Linezolid is a promising drug in children with tuberculosis who need the use of reserve drugs, since clinical efficacy is noted, MBT resistance is rarely developed, and the frequency of undesirable side reactions of regimens with the inclusion of linezolid does not exceed the frequency of those when prescribing regimens without the inclusion of linezolid

A reduced incidence of tuberculosis in infants has decreased the alertness of physicians to recognize complications in the course of the disease. Bronchopulmonary lesions, in fact, are a progression of primary tuberculosis and lead to aggravation of the disease, prolonging and complicating treatment. Often it is necessary to introduce standby drugs into the treatment regimen and to perform prolonged rehabilitation.