Basic descriptions of the rats liver microvasculature and its prognostic significance under development of pancreatitis of different severity were determined by arheography method. Increased nitric monoxide content in the rats entails even more pronounced reduction of a tone of the liver’s great vessels. The vessels of medium and small diameter are less influenced and the reductionwasshort-term. Using the rheohepatogramme indices makes possible to determine the disturbance of liver’shaemodynamicsunderthe hepatopathy development.