Prognozirovanie haraktera opuholej yaichnikov u beremennyh imeet vazhnoe klinicheskoe znachenie, no znachitel'no zatrudneno. V poslednie 5–10 let u neberemennyh v ginekologii predlozheno ispol'zovat' RMI (Risk of malignancy index), odnako v akusherskoj praktike cennost' etogo issledovaniya eshche ne ustanovlena. Cel'yu issledovaniya bylo opredelit' RMI-IV i RMI-V pri dooperacionnom neinvazivnom prognozirovanii haraktera opuholej yaichnikov u beremennyh. Retro i prospektivno otobrany dannye kliniko-laboratornogo obsledovaniya 114 beremennyh 20–38 let, iz kotoryh 15 pacientok imeli zlokachestvennye opuholi yaichnikov (ZOYA), 28 pacientok — pogranichnye opuholi yaichnikov (POYA) i 71 pacientka — dobrokachestvennye opuholi yaichnikov (DOYA). Provodili ul'trazvukovoe issledovanie (UZI) s ispol'zovaniem cvetovoj dopplerografii i impul'snovolnovoj dopplerometrii. Opredelyali koncentraciyu SA-125 s pomoshch'yu immunofermentnogo analiza. Dlya ocenki riska raka yaichnikov ispol'zovali modifikacii IV, V. V krovi beremennyh s ZOYA bylo vyyavleno umerennoe statisticheski ne znachimoe povyshenie SA-125 po sravneniyu s takovymi znacheniyami u pacientok s DOYA i POYA. Po sravneniyu s gruppoj beremennyh s DOYA, pacientki s POYA i ZOYA demonstrirovali povyshennyj uroven' RMI-IV i RMI-V. Dlya garantirovannogo razlichiya v diagnostike opuholej neobhodimy kraevye znacheniya (RMI-IV — vyshe 3500 ukazyvayut na ZOYA, nizhe 100 — na otsutstvie zlokachestvennogo processa). Dlya RMI-V analogichnymi znacheniyami yavlyayutsya 1500 i 60. Odnako dlya prinyatiya resheniya v bol'shinstve nablyudenij nalichiya tol'ko pokazatelej RMI-IV i RMI-V bylo nedostatochno i trebovalos' ispol'zovat' kompleksnyj podhod. Takim obrazom, opredelit' harakter novoobrazovanij yaichnikov u beremennyh trudno, esli ispol'zovat' tol'ko indeksy RMI. Dlya dooperacionnogo prognozirovaniya haraktera opuholej yaichnikov u beremennyh trebuetsya kompleksnoe klinicheskoe obsledovanie s ispol'zovaniem vizualizacionnyh metodov, primenenie modelej prognozirovaniya, uchityvayushchih bol'shoe kolichestvo opisatel'nyh «morfologicheskih» harakteristik opuholej.
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