The use of solutions of chlorhexidine for hygienic measures creates a number of side effects: change the color of the teeth and the mucous membranes, desquamation, taste disturbance, dysbiosis overgrowth in the mouth. These effects can lead to further aggravation of the condition, it limits the indications for long-term use of chlorhex-idine.At present preference is given to tools made of natural ingredients that contain vitamins, macro - and trace minerals, chlorophyll, volatile and other vital biologically active substances affect the metabolic processes. They have the positive anti-microbial, anti-inflammatory, hemostatic, healing and analgesic effects; they are not inferior in efficiency of synthetic drugs. At the same time they are safe, accessible and affordable, which is important for the elderly and senile age. In this paper a comparative characterization of the state of oral hygiene and denture in elderly patients with complete and partial loss of teeth is presented. Despite the high clinical and laboratory findings, the prepared tools are often not available for this group of patients for financial reasons. As result these patients not undertake any hygienic measures. The proposed hygienic means for rinsing the oral cavity and treatment dentures have low cost, available for most patients and have a high clinical efficacy, it is confirmed by microbiological methods.