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The article summarizes and analyzes the main impacts of various xenobiotics or their groups on the human body and the consequences of such exposure. The study suggests the refinements to the generally accepted classification of xenobiotics’ origins. The paper also describes the molecular mechanism of foreign substances biotransformation in a human body. The metabolism of xenobiotics differs due to their forms and types’ varieties. The factors of influence on chemicals’ metabolism are also of great importance. Individual features of the metabolism may be associated with genetic differences in the activity of metabolic enzymes. The research results further the comprehension of the exposure pathways and health impacts of the xenobiotics and their metabolites.

Xenobiotics - substances alien to the body - have become a major problem, since they negatively affect human health. They can directly affect, disrupting vital functions, and can form various metabolites in the body due to transformation. But the main danger of xenobiotics is their bioaccumulation. There are many studies on how to prevent the harmful effects of xenobiotics. This article discusses the main routes of ingestion of these foreign.

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