Abbreviations: CHD, coronary heart disease; CV, coefficient of variation; HOMA-IR, insulin resistance index of the homeostasis model assessment; RLP, remnant-like particle.A OBJECTIVE -The aim of the study was to investigate the relationships between remnantlike particle (RLP) cholesterol, triglycerides, and insulin resistance in nonobese Japanese type 2 diabetic patients. RESEARCH DESIGN AND METHODS-A total of 86 nonobese Japanese type 2 diabetic patients (72 men and 14 women, aged 40-83 years, BMI 20.1-26.6 kg/m 2 ) were studied. BMI, HbA 1c levels, and fasting concentrations of plasma glucose, serum lipids (RLP cholesterol, total cholesterol, HDL cholesterol, and triglycerides), and serum insulin were measured. Insulin resistance was estimated by the homeostasis model assessment (HOMA-IR). The subjects were divided into two groups according to the value of HOMA-IR. Values Ͼ2.5 were indicative of the insulin-resistant state, and values Ͻ2.5 were indicative of the insulin-sensitive state.RESULTS -The insulin-resistant group had significantly higher RLP cholesterol and triglyceride levels and lower HDL cholesterol levels compared with the insulin-sensitive group. Univariate regression analysis showed that insulin resistance was positively correlated with BMI (r = 0.254, P = 0.019), HbA 1c levels (r = 0.278, P = 0.011), RLP cholesterol levels (r = 0.315, P = 0.004), and triglyceride levels (r = 0.332, P = 0.002) and was negatively correlated with HDL cholesterol levels (r = Ϫ0.301, P = 0.006) in our diabetic patients. Multiple regression analysis showed that insulin resistance was independently associated with serum triglyceride levels, which explained 13.5% of the variability of insulin resistance in our nonobese Japanese type 2 diabetic patients.CONCLUSIONS -These results indicate that 1) nonobese Japanese type 2 diabetic patients with insulin resistance are characterized by high RLP cholesterol and triglyceride levels, and low HDL cholesterol levels; and 2) the level of serum triglycerides is an independent predictor of insulin resistance in these patients.

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Types topologiques des polynômes Publications mathématiques de l'I.H.É.S., tome 46 (1976), p. 87-106 © Publications mathématiques de l'I.H.É.S., 1976, tous droits réservés. L'accès aux archives de la revue « Publications mathématiques de l'I.H.É.S. » (http:// www.ihes.fr/IHES/Publications/Publications.html) implique l'accord avec les conditions générales d'utilisation (http://www.numdam.org/conditions). Toute utilisation commerciale ou impression systématique est constitutive d'une infraction pénale. Toute copie ou impression de ce fichier doit contenir la présente mention de copyright. Article numérisé dans le cadre du programme Numérisation de documents anciens mathématiques http://www.numdam.org/ î^y)=x{y+tx){x 2-^). 87 88 TAKUOFUKUDA En calculant le bi-rapport des droites x=o, y-\-tx=0y x-}-y=o et x-jy==o, on voit que le type différentiable de cette fonction varie continûment avec le paramètre t, c'est-à-dire que deux fonctions correspondant à des valeurs différentes du paramètre t ne sont pas de même type différentiable. Cet exemple nous montre que P(^, i, k; R)/n 'est plus fini. D'autre part, Thom [7] a donné un exemple qui montre que P(%, m, k; K)/n 'est pas fini en général pour m ^3 : Exemple 2 ([7]).-On considère l'application G(:R 3->R 3 , dépendant algébriquement du paramètre ty définie par les équations : X =(A:(^+y-û 2)-2ayz)\{ty +x) [x 2 +y-a 2)-2az[y-tx)Y, Y=^+y-û 2 , Z=z. Thom a montré que deux applications G^ et Gg, correspondant à deux valeurs différentes du paramètre t, ne sont pas de même type topologique. Le problème du cas où m==2 reste encore ouvert. On doit noter que R. Thom a écrit à l'auteur qu'il croit que dans ce cas aussi : Conjecture (diaprés R. Thom).-.[^ensemble P(^, 2, k\ K)/^ est un ensemble fini. Je remercie vivement M. René Thom pour les conversations que nous avons pu avoir ensemble et pour ses suggestions et encouragements. (0.3) Table des matières. Au premier chapitre on rappelle le lemme d'isotopie de Thom. Le deuxième chapitre est consacré à la stratification des morphismes algébriques. Ces lemmes d'isotopie et de stratification des morphismes algébriques sont les outils principaux de la démonstration de notre théorème i.

In recent years there has been significant worldwide activity in shared-use vehicle systems (i.e., carsharing and station cars). Much of this activity is taking place in Europe and North America; however, there has also been significant activity in Asia, primarily in Japan and Singapore. This paper examines the latest shared-use vehicle system activities in both of these countries, beginning with an historical review followed by an evaluation of their current systems. Overall there are several well-established systems in both Japan (approximately 18 systems, 150 vehicles, 3000 members) and Singapore (approximately 4 systems, 300 vehicles, and 8000 members). In contrast to most European and North American cities, both Japan and Singapore already have a wide range of viable public transportation modes. Interestingly, the primary carsharing focus in Japan is on business use and on neighborhood residential in Singapore. This is likely due to limited vehicle licensing and high car ownership costs in Singapore. Further, systems in Japan and Singapore have a high degree of advanced technology in their systems, making the systems both easy to use and manage. The member-vehicle ratios in Asia appear to be approximately the same as Europe and Canada and less than the U.S. It is expected that Asian shared-use vehicle systems will continue to have steady growth in terms of number of organizations, vehicles, and users.