The aim of the research was to determine how chronic obstructive lung disease clinical signs with lung ventilation function disturbance to various degrees correspond to respiration biomechanics and high resolution computed tomography indices. It was revealed that respiration biomechanics indices are changed at the early stages of chronic obstructive lung disease formation.

The aim of our research was analysis and comparison of chronic obstructive lung disease clinicalsigns and function indices of external respiration apparatus and inspiratory-expiratory high resolution computed tomography. 48 patients with chronic obstructive lung disease were examined. The importance of respiration biomechanics and inspiratory-expiratory high resolution computed tomography indices for diagnostics of broncho-obstruction at an early stage with unchanged forced expiration volume within the first second was revealed.

The aim of the research was comparison of clinical symptoms, respiration biomechanics indices of patients with chronic obstructive lung disease. It was revealed that respiration biomechanics indices are the earliest emphysema signs of patients with chronic obstructive lung disease in the period when the structure of total lung capacity is not changed.