It has been empirically known that androgenic hormonal administration deepens the voice of a patient with female-to-male gender identity disorder (FTM/GID). However, there have been few reports that evaluated its time-dependent change. Here we report the time-dependent changes in the speaking fundamental frequencies of 23 FTM/GID patients who were administered androgenic hormone. Vowel sounds produced in an effortless way were recorded at baseline and 1, 2, 3, 6, 9, and 12 months after the start of the administration of androgenic hormone, and the speaking fundamental frequencies were evaluated. The speaking fundamental frequency was most drastically lowered between 1 and 3 months and was significantly lowered until 6 months. Although it was further lowered slightly between
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