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Key words：Leukocytapheresis（LCAP）therapy, Henoch-Schönlein purpura nephritis（HSPN), extrarenal symptoms, Intestinal bleeding, Henoch-Schönlein purpura（HSP) 〈Abstract〉 Case 1：A 57-year-old man was admitted to our hospital with polyarthritis, purpura and edema on both legs, and colicky abdominal pain with bloody diarrhea after common cold-like symptoms. A laboratory examination revealed nephrotic syndrome. He was diagnosed with HSP by skin and kidney biopsies. Treatment was initially started with prednisolone 50 mg／day intravenously. Although purpura on the lower extremities and polyarthritis partially improved after 2 weeks, his abdominal pain with melena worsened. Leukocytapheresis（LCAP）using Cellsorba E column was performed a total of 7 times twice a week. Intestinal bleeding with extrarenal symptoms disappeared after LCAP therapy. However, this therapy was not effective for edema and proteinuria；therefore, methylprednisolone pulse therapy was performed for 3 days, followed by oral prednisolone with cyclosporin. A