Ischemic stroke is a common clinical disease with high morbidity, high mortality and high disability rate, accounting for 70%~80% of stroke. It is a serious threat to human health, and brings the family and society heavy burden. By means of combining constitution of TCM and clinical assistant examination can provide new direction for prevention and treatment of ischemic stroke, facing the present conduction-unsatisfactory prevention and treatment effect, the complicated pathogenesis. This essay analyzes and summarizes the recent advances in ischemic stroke, TCM constitution and intracranial vascular changes detected by transcranial Doppler, and the related research progress between them, and aims to investigate the correlation between TCM constitution and intracranial vascular changes detected by transcranial Doppler in ischemic stroke patients.