발효여과물이 함유된 화장수와 크림을 하루에 3회 피부염병변에 6주간 도포하도록 하였다. 그 결과 SCORAD 지수는 26.9±11.8에서 14.9 ±9.7로 감소(p<0.05), Total IgE(IU/mL)는 641.9±1294.6에서 565.8±1076.8로 감소, Eosinophil의 수 (ug/dL)는 246.7±203.5에서 203.3±130.7로 감소하였다(p<0.05). 피부수분함유량은 36.6±10.0에서 44.0±10.3로 증가 (p<0.01), 경피수분손실량(g/h/m²)은 16.7±5.1에서 15.4±8.7로 감소(p<0.05)하였으며, 피부 pH는 약산성을 유지하였다. 또한 의사 및 환자의 총괄유효성 평가도 증가되었다. Abstact Sixteen moderate atopic dermatitis patients were treated with applying toner and cream using estern medical herbs[Estern medical complex(Radix Glycyrrhizae, Radix Angelicae Dahuricae, Rhizoma Ligustici Chuanxiong, Fructus ponciri Seu Aurantii Immaturus, Radix Rehmanniae Praeparata, Radix Puerariae, Rhizoma Corydalis), Cypress, Green tea, Radix Astragali, Red ginseng, Syrup ferment, Apple ferment filtrate] on the atopic area 2-3 times per day for 6 weeks. After 6 weeks of study, the result was a decrease in SCORAD index(26.9±11.8 to 14.9 ±9.7(p<0.05)), IgE(641.9±1294.6 to 565.8±1076.8), Eosinophil count(246.7±203.5 to 203.3±130.7(p<0.05)) and TEWL(16.7±5.1 to 15.4±8.7(p<0.05)). And skin hydration was increased(36.6±10.0 to 44.0±10.3(p<0.01)) maintaining skin pH level. The patient;s and physician's global assessment also improved. Therefore, estern medical herbs may play a role in treatment of atopic dermatitis.

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Interest in the environment is rising in all the sectors of industry and culture. Even in the fashion industry, fashion designers have recently begun delivering messages on the environment.In particular, Issey Miyake has been constantly interested in environmental issues, and has been deemed as a designer who values practicality and universality in clothing. This study seeks to examine Issey Miyake's fashion from the perspective of an eco-friendly design. This research analyzed collections of Issey Miyake from 1980 to 2010 through photo works and www.firstview.com.The research method was to study 8 people who have professionalism in fashion design and have analyzed 201 works of Issey Miyake from 1980s to 2000s that have the characteristics of eco-friendly design. The results showed the following characteristics of eco-friendly design in Issey Miyake's fashion : naturality, simplicity, sustainability and transformability. First, Issey Miyake preferred natural materials and used Japan traditional dyeing that integrated modern techniques for naturality. Second, he expressed simplicity in his fashion by applying the least cutting and sewing in geometric panels. Third, he pursued sustainability with comfortable clothing that anyone could wear regardless of trend, age and body shape. Finally, he developed the A-POC system that eliminated the usual needs for cutting and sewing and tried transformability on clothing using buttons, strings, belts, zippers, and layered styling.

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