0232 Male breast cancer in Tripoli/Libya

elhabbash, manal mousa; Alwindi, A.M.

doi:10.1016/s0960-9776(09)70249-8

Cited by 3 publications

(7 citation statements)

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“…This younger age at diagnosis parallels the similarly younger age reported in Middle Eastern women afflicted with breast cancer and equally demonstrated in our FBC group. This finding is also present in the few series available from other neighboring countries looking at MaleBC (9–11).…”

Section: Discussionsupporting

confidence: 65%

“…This study is, as far as we know, the first attempt to characterize MaleBC within the Lebanese population, and represents an addition to the small available series tackling this rare neoplasm in the eastern basin of the Mediterranean (9–11). This is especially meaningful given the different epidemiology and more aggressive phenotypes of breast cancer affecting women in the Middle East (2,12,13).…”

Section: Discussionmentioning

confidence: 99%

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Clinicopathologic and Immunohistochemical Characteristics of Male Breast Cancer: A Single Center Experience

et al. 2011

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Male breast cancer (MaleBC) is a rare tumor that has been insufficiently described in the Middle East. The purpose of this study is to report the first MaleBC series in Lebanon, describing its clinicopathologic and immunohistochemical phenotype, and how it compares with MaleBC in the West and with female breast cancer in Lebanon and the Middle East. Forty-seven cases of MaleBC were reviewed. Results showed younger ages at presentation (62 years versus 67 years), higher incidence of lobular carcinoma (6% versus 1%), and more frequent p53 positivity and axillary node metastases in our series than in those reported about MaleBC. Other results such as higher estrogen receptor (ER) positivity and lower HER-2/neu over-expression were comparable to the literature. These findings suggest that MaleBC in our region may represent a biologically different tumor with potentially distinct prognostic and therapeutic implications.

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Section: Discussionsupporting

confidence: 65%

Section: Discussionmentioning

confidence: 99%

Clinicopathologic and Immunohistochemical Characteristics of Male Breast Cancer: A Single Center Experience

et al. 2011

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“…In 4 studies [16][17][18][19] the distribution by clinical staging comprised 606 patients; for 76 (13%) of these, no stage was provided. In those with a known stage, 67% of the cases were stage II to IV (stage II= 53%, stage III= 12% and stage IV= 2%), in other words, they had advanced tumours larger than 2 cm; stage I was described in 33% of the patients.…”

Section: Primary Studies (N=10 Studies)mentioning

confidence: 99%

“…In those with a known stage, 67% of the cases were stage II to IV (stage II= 53%, stage III= 12% and stage IV= 2%), in other words, they had advanced tumours larger than 2 cm; stage I was described in 33% of the patients. Nine studies [15][16][17][18][19][20][21][22][23] described the histological type (n=780) and the predominant type was invasive ductal carcinoma, representing 96% of the analysed data. Ductal carcinoma in situ (DCIS) accounted for only 2% of tumours, according to available information.…”

Section: Primary Studies (N=10 Studies)mentioning

confidence: 99%

Prognosis of Male Breast Cancer: A Systematic Review of the Literature

Bender

Bergmann

Thuler

2014

BJMMR

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“…It is like that of female breast cancers at equal stage [ 6 ]. The 5-year survival varies between 43 and 85% in western countries [ 6 , 12 ] against 7 and 63% in Africa [ 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Male breast cancer: diagnosis stages, treatment and survival in a country with limited resources (Burkina Faso)

et al. 2018

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BackgroundMale breast cancer is a rare and less known disease. Therapeutic modalities affect survival. In Burkina Faso, male breast cancers are diagnosed in everyday practice, but the prognosis at short-, middle-, and long-term remains unknown. The objective of this study is to study the diagnosis stages, therapeutic modalities, and 5-year survival in male breast cancer at the General Surgery Unit of Yalgado Ouedraogo University Hospital from 1990 to 2009.MethodsA cohort longitudinal study concerning cases of breast cancer diagnosed in man. Survival was assessed using the Kaplan–Meier method and survival curves were compared through the LogRank test.ResultsFifty-one cases of male breast cancer were followed-up, i.e., 2.6% of all breast cancers. Stages III and IV represented 88% of cases. Eleven patients (21.6%) were at metastatic stage. Patients were operated in 60.8% of cases. The surgery included axillary dissection in 25 (80.6%) out of 31 cases. Lumpectomy was performed on 6.5% of patients (2 cases). Fifteen (29.4%) and 11 (21.6%) patients underwent chemotherapy and hormonal therapy, respectively. The FAC protocol was mostly used. Radiation therapy was possible in two cases. The median deadline for follow-up was 14.8 months. A local recurrence was noticed in 3.2% of cases. The overall 5-year survival rate was 49.9%. The median survival was over 5 years for stages I and II. It was 54 down to 36 months for stages III and IV.ConclusionDiagnosis is late. The lack of immunohistochemistry makes it difficult to define the proportion of their hormonal dependence. Surgery is the basic treatment. Five-year survival is slow and the median survival depends on the diagnosis stage. It can be improved through awareness-raising campaigns and the conduct of individual screening.

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0232 Male breast cancer in Tripoli/Libya

Cited by 3 publications

References 0 publications

Clinicopathologic and Immunohistochemical Characteristics of Male Breast Cancer: A Single Center Experience

Clinicopathologic and Immunohistochemical Characteristics of Male Breast Cancer: A Single Center Experience

Prognosis of Male Breast Cancer: A Systematic Review of the Literature

Male breast cancer: diagnosis stages, treatment and survival in a country with limited resources (Burkina Faso)

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