1.7.8.17 Ferrocenes (Update 2014)

Abstract

This chapter is an update to the earlier Science of Synthesis Section 1.7.8 describing methods for the synthesis of ferrocenes. The focus is on the literature published between 2000 and early 2013. The main methods discussed are direct complexation of ligands, modification of cyclopentadienyl rings by electrophilic substitution or directed lithiation, and functional-group transformations in ferrocenyl side-chains. The access to nonracemic ferrocenes and to ferrocenes with configurationally defined side-chain chirality is discussed.