Optical communication networks are vital in the digital era, but data transmission becomes weak the longer the distance traveled by light. Erbium-Doped Fiber Amplifier (EDFA) technology is commonly used as an optical amplifier, but it still produces a small gain, Q-factor, and a significant noise figure. This study characterized the Hybrid Optical Amplifier (HOA) combinations that contain EDFA with various doped fibers. The characterization was performed through Optisystem software simulation by observing and analyzing the gain, noise of figure, and Q-factor generated by each doped fiber variant. The results showed that the combination of Ytterbium-doped Fiber produced the most significant gain of 15.83 dB, less noise figure of 5,661 dB, and a relatively high Q-factor of 35,615 at 1,550 nm. It indicates that the HOA combination is suitable and ideal for long-distance transmission in fiber optic communication network applications.