2020
DOI: 10.1016/j.ajog.2019.11.1211
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1199: Prenatal test predicting respiratory morbidity at birth among growth restricted infants: a prospective observational study

Abstract: OBJECTIVE: Partial and complete hydatidiform moles (PHM, CHM) are a common cause of pregnancy loss. To assess the frequency and nature of genomic imbalances, specifically polyploidy resulting in PHM and whole-genome uniparental disomy (WG-UPD) resulting in CHM, a comprehensive analysis of a large cohort of miscarriage samples was analyzed by single nucleotide polymorphism (SNP)-based chromosomal microarray (CMA). STUDY DESIGN: The CMA results for 21,342 miscarriage samples were analyzed for polyploidy and WG-U… Show more

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