1248 Procollagen Type Iii Propeptide Levels Among Preterm Infants in Neonatal Intensive Care Unit

Abstract

Objective: to assess whether Doppler velocimetry is predictive of neonatal outcome in bichorionic and monochorionic twin pregnancies complicated by intrauterine growth restriction.Methods: were collected retrospectively data of all twin pregnancies complicated by intrauterine growth restriction during the period between

Relation of Procollagen Type III Amino Terminal Propeptide Level to Sepsis Severity in Pediatrics

“…Similar to our findings in septic patients, serum concentration was increased in severely injured non-survivors and in those who had developed MOF. This agrees with the results reported by Said et al [ 20 ] and Zakynthinos et al [ 15 ].…”

“…In agreement with our findings, Said et al [ 20 ] assessed levels of PIIINP among preterm neonates and found that serum PIIINP was significantly higher in septic cases than in the controls. The highest levels were in the ventilated group, followed by the septic and grower groups.…”

“…In line with our findings, Gäddnäs et al [ 10 ] reported that maximal serum PIIINP concentrations during sepsis were higher in non-survivors compared with survivors, and in multiple organ failure (MOF) compared with multiple organ dysfunction syndrome (MODS). In addition, Said et al [ 20 ] and Zakynthinos et al [ 15 ] reported similar findings. In our research, there were positive correlations between PIIINP and CRP (r = 0.327; p = 0.004) and WBCs (r = 0.260; p = 0.024); their ability was studied with the ROC curve for the prediction of sepsis and showed an AUC for PIIINP equal to 0.883 with a combined sensitivity and specificity of 88% and 82% with a cut-off point of 103.3 ng/mL.…”