146. A Novel 3D Printed Sacrificial Material for the Development of Perfused Intricate Blood Vessel Structures

Sacrificial biomaterials in 3D fabrication of scaffolds for tissue engineering applications

“…25,26 To mitigate these issues, researchers tried various strategies, including modifying the material, looking for sacrificial material with better biocompatibility, updating the fabrication process to reduce residues, and designing new fabrication methods to avoid harmful processes to cells. 27,28 Second, a suitable degradation speed of sacrificial materials plays a crucial role in maintaining the fidelity of scaffold constructs and ensuring the scaffolds function properly. If the sacrificial material degrades too quickly, the scaffold's structural integrity may be compromised, while if it is too slow, it may impede tissue regeneration.…”