148 Activation of E2F transcription factors in cardiac hypertrophy

News from the European Society of Cardiology Congress in Vienna, August 30 to September 3, 2003

“…Activation of this pathway could theoretically be called upon to improve contractile function, and data were presented on the anti-apoptotic effect of this pathway (14). Novel links to hypertrophy and remodeling currently under investigation are the cell-cycle regulatory proteins that were shown to be activated by hypertrophic stimuli (15). The apoptotic pathways could also be a novel target to influence postinfarction remodeling.…”