1663 Outcome of Patients With Carcinoma of the Collecting Duct (Cdc)

Staehler, Michael; Ketting, Barbara; Nuhn, Philipp; Nordhaus, Cordula; Roosen, Alexander; Siegert, Sabine; Städler, Thomas; Cg, Stief

doi:10.1016/j.juro.2010.02.1466

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“…[4] It was reported in unilateral kidney, [5] and a cystic component was occasionally presented on imaging findings, [6] sometimes even presented as a renal cyst. [7] The clinical manifestations include hematuria, flank pain, weight loss, palpable abdominal mass and metastasis related symptoms.…”

Section: Introductionmentioning

confidence: 99%

Bilateral kidneys involvement of collecting duct carcinoma with cystic change

et al. 2019

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RationaleCollecting duct carcinoma (CDC) is a rare neoplasm arising from the collecting duct and should be distinguished from other renal cell carcinomas that mostly originated from the proximal tubular epithelium and tumors originated from the urothelium. It usually occurs in unilateral kidney, sometimes found with cystic change.Patient concernsWe present the case of a 53-year-old male suffering from repeated bilateral flank pain for 6 months, increased pain with dysuria for 5 days.DiagnosisUltrasound showed 2 similar hybrid echo masses in bilateral kidneys with enlarged lymph nodes surrounded, which accords with magnetic resonance imaging (MRI), and intraoperative biopsy reported malignancy.InterventionsAn exploratory operation was performed and the mass on the left kidney was removed, but pathological result reported collecting duct carcinoma according to the morphological features and immunohistochemical tests. Also postsurgery positron emission tomography-computed tomography (PET-CT) confirmed the mass on the left kidney is also a lesion of CDC.OutcomesThe patient refused chemotherapy and had an overall survival of 7 months.LessonsWe presented a case of CDC involving bilateral kidneys with cystic change; this is the first case of bilateral renal occurrence with cystic change to our knowledge. Because of CDC's rapid growth and the lack of effective adjuvant treatment after surgery, the prognosis is poor and the diagnosis should be made carefully.

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Section: Introductionmentioning

confidence: 99%