“…25,26,28 At least 4625 patients were enrolled across the studies; however, five of the included studies did not report the number of enrolled patients. 19,30,31,33,34 The target patient population varied considerably across the studies (Table 1). Some studies specified that they enrolled patients with specific EOL conditions, including advanced cancer, 9,11,29 advanced cancer/end-stage organ failure, 25 or advanced dementia/critical illness.…”