175 Pseudolarix acid B inhibits angiogenesis and reduces hypoxia-inducible factor 1alpha by promoting proteosome-mediated degradation

Optimization of extracellular glucan production from Pleurotus eryngii and its impact on angiogenesis

“…Ex vivo anti-angiogenic activity of extracellular polysaccharide was measured by CAM assay as described by Li et al [28] with minor modifications. A group of twenty 7-day-old fertilized eggs were incubated at 37.5 • C and 55% relative humidity.…”

Chorioallantoic membrane assays have been based on diffusion control—Problems arising with a diversity of mass transfers in egg white

“…Up to present, a huge number of documents had performed anti-angiogenic test with chorioallantoic membrane assay (CAM) [4][5][6][7][8][9][10][11][12]. Because of the presence of great variation in composition in egg white [13][14][15] and the diversity of chemical structures and polarity of the medicines tested [16], the question arises with "Can CAM accurately reflect the inherent response of a biological system to therapeutics with respect to angiogenic status?"…”