191: An Alternative Field Hemostatic Agent? Comparison of a New Chitosan Granule Dressing to Existing Chitosan Wafer, Zeolite and Standard Dressings, in a Lethal Hemorrhagic Groin Injury

Kozen, Buddy G.; Kircher, Sara S.; Henao, José Mario Mayorga; Godínez, Francisco Antonio Gutiérrez; Johnson, Andrew S.

doi:10.1016/j.annemergmed.2007.06.343

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“…It was reported that upon contact with anionic erythrocytes, the positively charge chitosan rapidly crosslinks, adhering strongly to the surface of the wound which accelerates concentration of coagulation factors and platelets at the bleeding site (Kozen et al, 2007). Furthermore, it was suggested that chitosan hemostasis may act independently from platelet function and the coagulation cascade (Finkielsztein et al, 1997).…”

Section: Resultsmentioning

confidence: 99%