2-Mercaptopyrimidine-functionalized mesostructured silicas to develop electrochemical sensors for a rapid control of scopolamine in tea and herbal tea infusions

Casado, Natalia; Morante‐Zarcero, Sonia; Pérez‐Quintanilla, Damián; Sierra, Isabel

doi:10.1016/j.microc.2020.104877

Cited by 9 publications

(1 citation statement)

References 35 publications

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“…For example, the application of mesostructured silicas as new sorbents has been increased recently for food sample preparation, due to the advantages that they offer in terms of their textural characteristics, such as ordered structure with controlled pore size, large specific surface area and pore volume. In addition to the high chemical, mechanical and thermal stability, these silicas can be easily functionalized with organic ligands [ 29 , 30 , 31 , 32 ] or combined with other functional materials [ 33 , 34 , 35 ], which allows for its application for different purposes. In this sense, Santa Barbara Amorphous-15 (SBA-15) has been the main hexagonal mesostructured silica employed as sorbent for sample preparation.…”

Section: Introductionmentioning

confidence: 99%

Mesostructured Silicas as Cation-Exchange Sorbents in Packed or Dispersive Solid Phase Extraction for the Determination of Tropane Alkaloids in Culinary Aromatics Herbs by HPLC-MS/MS

González-Gómez

Casado

Morante‐Zarcero

et al. 2022

Toxins

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In this work, Hexagonal Mesoporous Silica (HMS) and Santa Barbara Amorphous-15 (SBA-15) mesostructured silicas were synthesized and functionalized with sulfonic acid groups. The materials (HMS-SO3− and SBA-15-SO3−) were evaluated as strong cation exchange sorbents for sample extract clean-up, by solid phase extraction (SPE) and dispersive solid phase extraction, to determine atropine (At) and scopolamine (Sc) in commercial culinary aromatic herbs. Under optimized conditions, 0.25 g of sample was subject to solid–liquid extraction with acidified water (pH 1.0), and good recovery percentages were achieved for At and Sc using 75 mg of HMS-SO3− in SPE as the clean-up stage, prior to their determination by HPLC-MS/MS. The proposed method was validated in a thyme sample showing recoveries in the range of 70–92%, good linearity (R2 > 0.999), adequate precision (RSD ≤ 14%) and low limits (MDL 0.8–2.2 µg/kg and MQL 2.6–7.2 µg/kg for both analytes). Sixteen aromatic herbs samples (dried thyme, basil and coriander leaves) were analysed and At was found in fourteen samples over an interval of <5–42 μg/kg, whereas Sc was found in three of the sixteen samples studied (between <5–34 μg/kg). The amount of At and Sc found in some analysed samples confirms the importance of setting maximum levels of At and Sc in culinary aromatic herbs.

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