2018 Guidelines for the management of dyslipidemia

Rhee, Eun Jung; Kim, Hyeon Chang; Kim, Jae Hyun; Lee, Eun Young; Kim, Byung Jin; Kim, Eun Mi; Song, YoonJu; Lim, Jeong Hyun; Kim, Hae Jin; Choi, Sang Yong; Moon, Min Kyong; Na, Jin Oh; Park, Kwang‐Yeol; Oh, Mi Sun; Han, Sang Youb; Noh, Junghyun; Yi, Kyung Hee; Lee, Sang Hak; Hong, Soon Cheol; Jeong, In Kyung

doi:10.3904/kjim.2019.188

Cited by 163 publications

(148 citation statements)

References 207 publications

(247 reference statements)

Supporting

Mentioning

137

Contrasting

Unclassified

Order By: Relevance

“…Our results also align with known lipid trajectories with biological aging; the Korean national data also showed that the mean levels of all serum lipid levels in women increased without upper threshold with aging, even exceeding that of men after sixth decade [27]. Hitherto, current treatment and surveillance guidelines highly advise precaution for elevated lipid levels among middle-aged and elderly women [19,20,28]. Furthermore, older adults were less likely to correctly recognize target blood pressure and cholesterol levels, suggesting insufficient awareness of cardiovascular risks for punctual management [29].…”

Section: Discussionsupporting

confidence: 86%

“…In this analysis, we presented the distribution of TG in its logarithmic form due to skewed distribution. Dyslipidemia was defined based on the 2018 Korean Dyslipidemia Treatment Guideline [19], which is equivalent to the Adult Treatment Panel III guidelines [20]. Hypercholesterolemia was defined as TC ≥240 mg/dL; hypertriglyceridemia was defined as TG ≥200 mg/dL; hypoalphalipoproteinemia was defined as HDLC < 40 mg/dL; hyper-LDLcholesterolemia was defined as LDLC ≥160 mg/dL.…”

Section: Definition Of Dyslipidemiamentioning

confidence: 99%

“…Sensitivity analyses were conducted by using lower LDLC cutoffs in the context of secondary prevention. Specifically, we referred to the 2018 Korean dyslipidemia guidelines [19] and the 2019 European Society of Cardiology/European Atherosclerosis Society guidelines for the management of dyslipidemia's 21 target LDLC ≥130 mg/dL for persons with low ASCVD risk and LDLC ≥116 mg/dL for moderate ASCVD risk. Those within these elevated LDLC ranges are recommended lifestyle modification or/and initiation/intensification of pharmacological treatment.…”

Section: Statistical Analysesmentioning

confidence: 99%

See 2 more Smart Citations

Associations between age and dyslipidemia are differed by education level: The Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) cohort

et al. 2020

Self Cite

View full text Add to dashboard Cite

Background: Dyslipidemia is a multifactorial disorder, which arises from complex interactions among genetic and environmental risk factors. Previous studies have established the deteriorating effect of aging on lipid profiles. However, little is known about the role of education level, a stable marker of socioeconomic status, which reflect modifiability of lifestyle risk factors. Therefore, we examined the association between age and individual dyslipidemia parameter across education level among healthy, middle-aged Korean women. Methods: From 2049 middle-aged women, education attainment was classified into completion of elementary school or below, middle school, high school, college or above. Dyslipidemia was assessed in adherence to the 2018 Korean Dyslipidemia Treatment Guideline. Multivariable logistic regression and generalized linear model tested for associations between age and dyslipidemia parameter across education level and other known risk factors, including menopause, obesity, and current drinking and smoking. Results: In this cross-sectional analysis, the prevalence of each dyslipidemia parameter was significantly different by age and education level. The odds ratio (OR) for dyslipidemia was higher among participants who were older and had received higher education (OR = 2.31, p for interaction = 0.008) than younger and low education counterpart. The interaction between age and education level remained significant for hypercholesterolemia (p for interaction = 0.003) and hyper-LDL-cholesterolemia (p for interaction = 0.002). Conclusions: Separate examination of individual dyslipidemia parameter indicated varying degree of interaction with age and education level. Such results imply that each type of lipid abnormality may arise from and be exacerbated by heterogeneous composition of biological and lifestyle risk factors, which may be reflected by education level.

show abstract

Section: Discussionsupporting

confidence: 86%

Section: Definition Of Dyslipidemiamentioning

confidence: 99%

Section: Statistical Analysesmentioning

confidence: 99%

See 1 more Smart Citation

Associations between age and dyslipidemia are differed by education level: The Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) cohort

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…Dyslipidemia is one of the prominent risk factors of the progression of atherosclerosis, which is an underlying cause of CVD [16]. Emerging evidence revealed that the MD diet has a protective effect against dyslipidemia and CVD [4,[31][32][33].…”

Section: Discussionmentioning

confidence: 99%

“…Due to the nature of a traditional Korean diet, the prevalence of obesity is relatively lower in South Korea than that in Western countries [15]. However, with rapid economic growth and the introduction of Western culture, the prevalence rate of hypercholesterolemia in adults aged above 30 years in South Korea has risen consistently up to 20%, and the prevalence rate of dyslipidemia has increased to 40.5% [16]. These trends have led to an increase in obesity and CVD.…”

Section: Introductionmentioning

confidence: 99%

Development and Validation of a Questionnaire to Measure Adherence to the Mediterranean Diet in Korean Adults

et al. 2020

View full text Add to dashboard Cite

The Mediterranean diet (MD) has beneficial effects on cardiovascular diseases, cancer, and mortality. Although various attempts have been made for estimating adherence to the MD using diet quality indices, few studies involving validated questionnaires for estimating adherence have been performed in Asian populations. We aimed to develop and validate the Korean version of the Mediterranean Diet Adherence Screener (K-MEDAS) by including 211 participants that visited health check-up centers and 116 participants with overweight or hypercholesterolemia that visited obesity clinic. The participants completed both the K-MEDAS and a 106-item food frequency questionnaire (FFQ). We translated 13 questions and developed 1 question. Considering the agreement between the K-MEDAS and FFQ, nine of the 14 questions showed moderate or high kappa values (≥0.4). The total MD scores measured by the K-MEDAS and FFQ showed substantial concordance (intraclass correlation coefficient = 0.678, 95% confidence interval: 0.520, 0.785). Multiple linear regression analyses revealed significant inverse associations between MD score and the levels of serum total cholesterol, low-density lipoprotein cholesterol, and non-high-density lipoprotein cholesterol, after adjusting for confounding variables. We found that K-MEDAS is valid tool for assessing adherence to the MD in the Korean population.

show abstract

Underweight status and development of end‐stage kidney disease: A nationwide population‐based study

Kim

Suh

et al. 2023

J cachexia sarcopenia muscle

View full text Add to dashboard Cite

BackgroundUnderweight status increases the risk of cardiovascular disease and mortality in the general population. However, whether underweight status is associated with an increased risk of developing end‐stage kidney disease is unknown.MethodsA total of 9 845 420 participants aged ≥20 years who underwent health checkups were identified from the Korean National Health Insurance Service database and analysed. Individuals with underweight (body mass index [BMI] < 18.5 kg/m2) and obesity (BMI ≥ 25 kg/m2) were categorized according to the World Health Organization recommendations for Asian populations.ResultsDuring a mean follow‐up period of 9.2 ± 1.1 years, 26 406 participants were diagnosed with end‐stage kidney disease. After fully adjusting for other potential predictors, the moderate to severe underweight group (<17 kg/m2) had a significantly higher risk of end‐stage kidney disease than that of the reference (normal) weight group (adjusted hazard ratio, 1.563; 95% confidence interval, 1.337–1.828), and competing risk analysis to address the competing risk of death also showed the similar results (adjusted hazard ratio, 1.228; 95% confidence interval, 1.042–1.448). Compared with that of the reference BMI group (24–25 kg/m2), the adjusted hazard ratios for end‐stage kidney disease increased as the BMI decreased by 1 kg/m2. In the sensitivity analysis, sustained underweight status or progression to underweight status over two repeated health checkups, when compared with normal weight status, had a higher hazard ratio for end‐stage kidney disease.ConclusionsUnderweight status is associated with an increased risk of end‐stage kidney disease, and this association gradually strengthens as BMI decreases.

show abstract

2018 Guidelines for the management of dyslipidemia

Cited by 163 publications

References 207 publications

Associations between age and dyslipidemia are differed by education level: The Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) cohort

Associations between age and dyslipidemia are differed by education level: The Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) cohort

Development and Validation of a Questionnaire to Measure Adherence to the Mediterranean Diet in Korean Adults

Underweight status and development of end‐stage kidney disease: A nationwide population‐based study

Contact Info

Product

Resources

About