2021_8_2

Verma, Tarun; Anurag, Tiwari; Yugal, Karkhur; Kumar, Raj; Maini, Lalit

doi:10.1016/j.jajs.2021.02.008

Cited by 4 publications

(6 citation statements)

References 24 publications

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“…Recommendations for UV light to be installed in air conditioning ducting overlook that most transmission occurs in the immediate proximity to infected people. High‐efficiency particulate air (HEPA) filters are a cost‐effective means of control to supplement ventilation and can be used with AGPs and when negative pressure rooms are not available, but with a requirement for increased maintenance and changing of filters 119,157–159 …”

Section: Workplace Ventilationmentioning

confidence: 99%

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COVID‐19 infection and the broader impacts of the pandemic on healthcare workers

et al. 2022

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The severe acute respiratory syndrome coronavirus (SARS‐CoV‐2) disease or COVID‐19 pandemic is associated with more than 230 million cases and has challenged healthcare systems globally. Many healthcare workers (HCWs) have acquired the infection, often through their workplace, with a significant number dying. The epidemiology of COVID‐19 infection in HCWs continues to be explored, with manifold exposure risks identified, leading to COVID‐19 being recognised as an occupational disease for HCWs. The physical illness due to COVID‐19 in HCWs is similar to the general population, with some HCWs experiencing a long‐term illness, which may impact their ability to return to work. HCWs have also been affected by the immense workplace and psychosocial disruption caused by the pandemic. The impacts on the psychological well‐being of HCWs globally have been profound, with high prevalence estimates for mental health symptoms, including emotional exhaustion. Globally, governments, healthcare organisations and employers have key responsibilities, including: to be better prepared for crises with comprehensive disaster response management plans, and to protect and preserve the health workforce from the physical and psychological impacts of the pandemic. While prioritising HCWs in vaccine rollouts globally has been critical, managing exposures and outbreaks occurring in healthcare settings remains challenging and continues to lead to substantial disruption to the health workforce. Safeguarding healthcare workforces during crises is critical as we move forward on the new path of ‘COVID normal’.

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Section: Workplace Ventilationmentioning

confidence: 99%

“…High-efficiency particulate air (HEPA) filters are a cost-effective means of control to supplement ventilation and can be used with AGPs and when negative pressure rooms are not available, but with a requirement for increased maintenance and changing of filters. 119,[157][158][159]…”

Section: Workplace Ventilationmentioning

confidence: 99%

COVID‐19 infection and the broader impacts of the pandemic on healthcare workers

et al. 2022

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“…Rather than road traffic accidents, domestic trauma seemed to have stood out during the pandemic period especially falls from any height involving the elderly due to the long period of social distancing and domestic confinement [ 16 , 19 ]. On top of that, the presence of comorbidities and the severe co-infection by SARS-CoV-2 virus also became important risk factors for FRI in this population, according to the multicenter study by McDonald et al [ 20 ].…”

Section: Discussionmentioning

confidence: 99%

Prior use of antibiotics and immunosuppression are risk factors for fracture-related infection during the COVID-19 pandemic period: a Brazilian prospective cohort study

Santos

Prebianchi

Santos

et al. 2022

BMC Musculoskelet Disord

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Background Little is known about the role of COVID-19 pandemic period on the epidemiology of fracture-related infection (FRI). The present study summarizes the changes in the prevalence, microbiology, and risk factors of FRI during this period. Methods A prospective single-center cohort study assessed in the setting of COVID-19 pandemic (2020–2021), clinical, microbiological aspects, and independent risk factors (RF) of FRI. RFs were estimated by bivariate and multivariable analyses using prevalence ratio (PR) with significance at P < 0.05. Kaplan–Meier analysis was performed to evaluate treatment outcomes. Results Overall, 132 patients were analyzed, with patients with age over 65 years accounting 65.1%. FRI was diagnosed in 21(15.9%) patients. Independent RFs for FRI were recent and preoperative use of systemic antibiotics (PR: 7.0, 95% confidence interval (95% CI): 2.2 – 22.4, p = 0.001) and cancer (PR: 9.8, 95% CI: 2.0 – 48.8, p = 0.005). Cultures yielded Gram-negative bacteria in 77.8%, 33.3% were MDR. Conclusions We found higher rates of FRI, predominating in the elderly with closed femoral fractures during the COVID-19 pandemic. Prior use of antibiotics and immunosuppression conditions were independent factor for FRI. Our outcomes provide evidence to avoid the empirical use of antibiotics prior to surgery for fracture stabilization.

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“…Orthopedic surgery strictly requires the sterility of implants and environment. The positive pressure environment of the operating room can also greatly reduce the risk of bacterial contamination of the surgical site (Tarun et al, 2021). However, if the aseptic operation is not performed properly, bacteria will directly accumulate on the surface of the implant through the surgical wound or the air during the operation.…”

Section: Causes Of Oiaimentioning

confidence: 99%

Recent Progress in antibacterial hydrogel coatings for targeting biofilm to prevent orthopedic implant-associated infections

Wang,

Zheng,

Yin

et al. 2023

Front. Microbiol.

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The application of orthopedic implants for bone tissue reconstruction and functional restoration is crucial for patients with severe bone fractures and defects. However, the abiotic nature of orthopedic implants allows bacterial adhesion and colonization, leading to the formation of bacterial biofilms on the implant surface. This can result in implant failure and severe complications such as osteomyelitis and septic arthritis. The emergence of antibiotic-resistant bacteria and the limited efficacy of drugs against biofilms have increased the risk of orthopedic implant-associated infections (OIAI), necessitating the development of alternative therapeutics. In this regard, antibacterial hydrogels based on bacteria repelling, contact killing, drug delivery, or external assistance strategies have been extensively investigated for coating orthopedic implants through surface modification, offering a promising approach to target biofilm formation and prevent OIAI. This review provides an overview of recent advancements in the application of antibacterial hydrogel coatings for preventing OIAI by targeting biofilm formation. The topics covered include: (1) the mechanisms underlying OIAI occurrence and the role of biofilms in exacerbating OIAI development; (2) current strategies to impart anti-biofilm properties to hydrogel coatings and the mechanisms involved in treating OIAI. This article aims to summarize the progress in antibacterial hydrogel coatings for OIAI prevention, providing valuable insights and facilitating the development of prognostic markers for the design of effective antibacterial orthopedic implants.

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2021_8_2

Cited by 4 publications

References 24 publications

COVID‐19 infection and the broader impacts of the pandemic on healthcare workers

COVID‐19 infection and the broader impacts of the pandemic on healthcare workers

Prior use of antibiotics and immunosuppression are risk factors for fracture-related infection during the COVID-19 pandemic period: a Brazilian prospective cohort study

Recent Progress in antibacterial hydrogel coatings for targeting biofilm to prevent orthopedic implant-associated infections

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