2012
DOI: 10.1016/s0016-5085(12)60194-2
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205 MicroRNA Expression Profiling Identifies MiR-328 Regulates Cancer Stem Cell-Like SP Cells in Colorectal Cancer

et al.

Abstract: BACKGROUND: Side population (SP) cells and their relationship to stem cell-like properties have been insufficiently studied in colorectal cancer (CRC). MicroRNAs (miRNAs) have attracted much attention but their roles in the maintenance of SP phenotype remain unclear. METHODS: The SPs from CRC cell lines and primary cell cultures were analysed for stem cell-like properties. MiRNA microarray analysis identified miR-328 as a potential stemness miRNA of SP phenotype. The level of miR-328 expression in clinical sam… Show more

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