28 nm PARTICLES IN FÆCES IN INFANTILE GASTROENTERITIS

Madeley, C. R.; Cosgrove, B.

doi:10.1016/s0140-6736(75)90858-2

Cited by 355 publications

(224 citation statements)

References 1 publication

Supporting

Mentioning

212

Contrasting

Unclassified

Order By: Relevance

“…Reports of symptomless excretion have been made but less frequently and usually in newborns (Chrystie et al 1975;Murphy, Albrey & Crewe, 1977). Astroviruses, though less commonly reported, show a similar association with disease (Madeley & Cosgrove, 1975;Kurtz, Lee & Pickering, 1977). Our own results, to be published, show that both viruses show an approximate 80 % association with symptoms although with neither virus does the rate approach 100 %.…”

Section: Discussionmentioning

confidence: 51%

Stool viruses in babies in Glasgow: 2. Investigation of normal newborns in hospital

Madeley

Cosgrove

Bell

1978

J. Hyg.

View full text Add to dashboard Cite

SummaryThe stools of 37 newborn babies born in hospital were examined for the presence of virus. An extract of every stool passed by each baby was examined in the electron microscope and inoculated into cell cultures. The babies were delivered in four separate maternity units (A–D). All the babies from units A and C (9 babies) were found to be excreting rotavirus though none showed any evidence of diarrhoea. Two of the babies also excreted astrovirus. Subsequently unit A was closed for cleaning and, on reopening with more restrictions on visitors, a further 19 babies were examined. No virus was found in any of their stools, nor was virus observed in the stools of babies from units B and D, where visiting was also more restricted. Visiting restrictions in these units excluded older siblings of the babies. No virus was cultured from any stools in this study.

show abstract

Section: Discussionmentioning

confidence: 51%

Stool viruses in babies in Glasgow: 2. Investigation of normal newborns in hospital

Madeley

Cosgrove

Bell

1978

J. Hyg.

View full text Add to dashboard Cite

show abstract

“…The name astrovirus comes from ''astron'' (Greek for star) describing the star-like morphology visualized by electron microscopy (Madeley & Cosgrove, 1975). Astroviruses cause, in most species, problems such as gastroenteritis and growth depression.…”

Section: Introductionmentioning

confidence: 99%

Detection and characterization of a new astrovirus in chicken and turkeys with enteric and locomotion disorders

Wit

Dam²,

Laar³

et al. 2011

Avian Pathology

View full text Add to dashboard Cite

In the present paper, we report the unexpected discovery of a new virus in samples from chicken and turkey flocks with clinical disorders such as tenosynovitis, enteric problems, or runting and/or stunting-like conditions. Since 1987, several virus isolation attempts on samples from these flocks resulted in the same macroscopic characteristic lesions in embryonated specific pathogen free eggs, being mortality with brightred discolouration of legs and wing-tips, a swollen dark-red liver and oedema. Initial work suggested the presence of an agent with characteristics of a non-enveloped RNA virus. Further work, which is described in this paper, showed that the isolated strains formed a new group of avian nephritis viruses, which is genetically and antigenically distinct from known avian astroviruses. Inoculation of a representative strain (isolate 19) of this new group of avian nephritis viruses, provisionally named avian nephritis virus-3, in specific pathogen free layer chicks resulted in diarrhoea, runting and stunting, and even mortality.

show abstract

“…Astrovirus was first described in 1975 as the result of electron microscopy (EM) studies in the UK on faeces from children with diarrhoea [1][2][3]. During the following decade astroviruses were experimentally transmitted in adult volunteers [4], propagated in human embryonic kidney cells [5] and serially passaged in a continuous line of monkey kidney cells, LLCMK2 [6].…”

Section: Introductionmentioning

confidence: 99%

Identification of astrovirus serotypes from children treated at the Hospitals for Sick Children, London 1981–93

Noel

Cubitt

1994

Epidemiol. Infect.

View full text Add to dashboard Cite

SUMMARYAn enzyme immunoassay (EIA) for astrovirus type 1 together with immune electronmicroscopy (IEM) was used to type a collection of 162 astroviruses obtained from 1981-93 from children with diarrhoea. The EIA was found to be specific for astrovirus type 1. Astrovirus types 2-4 were typed by IEM.Astrovirus type 1 was the prevalent serotype 107/125 (86 %), followed by type 3 (8 %), type 4 (6 %) and type 2 (1 %). Six samples containing astrovirus could not be typed or detected by EIA because they were coated with coproantibodies; 11 others were not identified. Virus particles could no longer be detected in 15/162 (9%) samples following storage for > 2 years.

show abstract

28 nm PARTICLES IN FÆCES IN INFANTILE GASTROENTERITIS

Cited by 355 publications

References 1 publication

Stool viruses in babies in Glasgow: 2. Investigation of normal newborns in hospital

Stool viruses in babies in Glasgow: 2. Investigation of normal newborns in hospital

Detection and characterization of a new astrovirus in chicken and turkeys with enteric and locomotion disorders

Identification of astrovirus serotypes from children treated at the Hospitals for Sick Children, London 1981–93

Contact Info

Product

Resources

About