2024
DOI: 10.1002/adma.202312316
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2D Catalytic Nanozyme Enables Cascade Enzyodynamic Effect‐Boosted and Ca2+ Overload‐Induced Synergistic Ferroptosis/Apoptosis in Tumor

Zeyu Wang,
Xue Wang,
Xinyue Dai
et al.

Abstract: The introduction of glucose oxidase, exhibiting characteristics of glucose consumption and H2O2 production, represents an emerging antineoplastic therapeutic approach that disrupts nutrient supply and promotes the efficient generation of reactive oxygen species (ROS). However, the instability of natural enzymes and their low therapeutic efficacy significantly impede their broader application. In this context, we present two‐dimensional Ca2Mn8O16 nanosheets (CMO NSs) designed and engineered to serve as a high‐p… Show more

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Cited by 16 publications
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