2P-288 Development of database for protein-protein interaction sites(The 46th Annual Meeting of the Biophysical Society of Japan)

Abstract

protocols such as mutage"esis A gupport Vector Machinc has btLn apphed zo trainmg modelg on a dataset of Sl RNA bindnig protcms irom the ?DB (RNAsct81) Ngodels have been created usmg diffeTent LombmaUons of featuTes posrtioll specific scormg matrix residue mteiface propenstty predicted acceggiblhty and hydrophob]city over overldppmg subsequenLes of iarious lengthg The method achieves a Mattheus Correlation Coeffictent (MCC) ofe 50 and an Area under a ReLcivei Operator Characte"stie (AUC) ofe g6 m a 5 told cTosg vahddtlon