3 Tesla magnetic resonance imaging of the prostate with combined pelvic phased-array and endorectal coils

Management decisions for patients with prostate cancer present a dilemma for both patients and their clinicians because prostate cancers demonstrate a wide range in biologic activity, with the majority of cases not leading to a prostate cancer related death. Furthermore, the current treatment options have significant side effects, such as incontinence, rectal injury and impotence. Key elements for guiding appropriate treatment include: distinction of organ-confined disease from extracapsular extension (ECE); and determination of tumor volume and tumor grade, none of which have been satisfactorily accomplished in today's pre-treatment paradigm. Magnetic resonance imaging (MRI) has the capability to assess prostate tissue, both functionally and morphologically. MRI as a staging tool has not shown enough consistency or sufficient accuracy for widespread adoption in clinical practice; yet, recent technical developments in MRI have yielded improved results. At our institution we have combined the use of new endorectal 3 Tesla MRI technology, T2-weighted, and high spatial resolution dynamic-contrast enhanced (DCE) MRI to non-invasively assess the prostate with higher signal-to-noise ratio and spatial resolution than previously achieved. This approach allows assessment of prostate-tissue morphology and kinetics, thus providing a non-invasive tool for tumor detection and staging and, consequently, directing biopsy and treatment specifically to diseased areas for a pre-treatment evaluation that can assist in the rational selection of patients for appropriate prostate cancer therapy.

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“…This paves the way for dynamic studies with high pathoanatomic detail at an optimal temporal resolution for kinetic analysis. [37] …”

Section: Temporal and Spatial Resolution In Dce Mrimentioning

confidence: 99%

“…The excellent spatial resolution achieved with endorectal coil 3T MRI with at least halving the voxel size (voxel size, 0.35 mm3 v 0.66-1.12 mm3), reveals pathoanatomic details on T2-W images not seen at 1.5T or 3T without endorectal coil. [37] …”

Section: T2-weighted (T2w) Mrimentioning

confidence: 99%

The role of magnetic resonance imaging (MRI) in prostate cancer imaging and staging at 1.5 and 3 Tesla: The Beth Israel Deaconess Medical Center (BIDMC) approach

Bloch

Lenkinski

Rofsky

2008

CBM

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“…3T MRI has been available for diagnosis of prostate cancer, and its merits have been reported in [4,5,6]. However, the application of high-field closed-bore MRI to prostate intervention is still limited, because of its limited access to the patient.…”

Section: Introductionmentioning

confidence: 99%

Software Strategy for Robotic Transperineal Prostate Therapy in Closed-Bore MRI

Tokuda

Fischer

Csoma

et al. 2008

Medical Image Computing and Computer-Assisted Intervention – MICCAI 2008

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A software strategy to provide intuitive navigation for MRI-guided robotic transperineal prostate therapy is presented. In the system, the robot control unit, the MRI scanner, and open-source navigation software are connected to one another via Ethernet to exchange commands, coordinates, and images. Six states of the system called "workphases" are defined based on the clinical scenario to synchronize behaviors of all components. The wizard-style user interface allows easy following of the clinical workflow. On top of this framework, the software provides features for intuitive needle guidance: interactive target planning; 3D image visualization with current needle position; treatment monitoring through real-time MRI. These features are supported by calibration of robot and image coordinates by the fiducial-based registration. The performance test shows that the registration error of the system was 2.6 mm in the prostate area, and it displayed real-time 2D image 1.7 s after the completion of image acquisition.

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“…However, the SNR increase provided by an ERC can only be partially replaced by a two-fold SNR improvement associated with doubling the magnet strength. Nevertheless, with advances in pulse sequence design, several groups reported that studies done solely with 6 to 32 phased array surface coils at 3T yielded comparable images as the exams conducted with 1.5T scanners with an endorectal coil [35][36][37][38][39]. Comparison studies with and without ERC at 3T have shown increased sensitivity (0.45, no ERC and 0.75, with ERC) and positive predictive value (0.64, no ERC and 0.80, ERC) for prostate cancer detection [40] (Fig.…”

Section: Hardware and Software Considerationsmentioning

confidence: 99%

Practical aspects of prostate MRI: hardware and software considerations, protocols, and patient preparation

et al. 2015

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The use of multiparametric MRI scans for the evaluation of men with prostate cancer has increased dramatically and is likely to continue expanding as new developments come to practice. However, it has not yet gained the same level of acceptance of other imaging tests. Partly, this is because of the use of suboptimal protocols, lack of standardization, and inadequate patient preparation. In this manuscript, we describe several practical aspects of prostate MRI that may facilitate the implementation of new prostate imaging programs or the expansion of existing ones.

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3 Tesla magnetic resonance imaging of the prostate with combined pelvic phased-array and endorectal coils

Cited by 57 publications

References 11 publications

The role of magnetic resonance imaging (MRI) in prostate cancer imaging and staging at 1.5 and 3 Tesla: The Beth Israel Deaconess Medical Center (BIDMC) approach

The role of magnetic resonance imaging (MRI) in prostate cancer imaging and staging at 1.5 and 3 Tesla: The Beth Israel Deaconess Medical Center (BIDMC) approach

Software Strategy for Robotic Transperineal Prostate Therapy in Closed-Bore MRI

Practical aspects of prostate MRI: hardware and software considerations, protocols, and patient preparation

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