310 The Evaluation of the Emergency Department GoodRx Prescription Discount Card Distribution Program

Abstract

appropriate antibiotic selection with a total of 5,062 patients. Comparator groups for intervention were hours without a pharmacist present in 6 studies, pre-protocol implementation in 9 studies, and alternative provider culture follow-up in 9 studies. Pharmacist involvement in stewardship was associated with a greater likelihood of receiving appropriate antibiotics (OR 3.23; 95% CI 1.98, 5.27). Among methods of intervention, pharmacist presence in the ED (OR 3.13; 95% CI 2.27, 4.32) and pharmacist-led algorithm and education (OR 6.13; 95% CI 2.85, 13.18) were associated with appropriate antibiotics. Pharmacist-led culture review was not significantly associated (OR 1.89; 95% CI 0.88, 4.06). Heterogeneity was high for all assessments.Conclusion: Though the overall quality of evidence was low, it appears that pharmacist involvement in antibiotic stewardship in the ED may significantly improve appropriate antibiotic selection. Pharmacist presence in the ED and pharmacist-led algorithm and education development may have a greater impact than pharmacist-led culture review.