345 Transepithelial Brush Biopsy With Computer-Assisted Tissue Analysis Increases Detection of Residual or Recurrent Intestinal Metaplasia and Dysplasia Following Endoscopic Ablation of Barrett's Esophagus

Iorio, Natalya; Sprung, Brandon; Kaul, Vivek; Marino, Danielle; Kothari, Shivangi; Kothari, Truptesh; Kataria, Rahul; Gross, Seth A.; Smith, Michael S.

doi:10.1016/j.gie.2015.03.1222

Cited by 3 publications

(1 citation statement)

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“…and the chair of the Standards of Practice committee (S.W.). For Anandasabapathy et al, 102 Johanson et al, 107 and Iorio et al, 104 the outcome reported was dysplasia. The manufacturer confirmed that indefinite for dysplasia was excluded from the analyses in 2 of the 3 studies.…”

Section: Question 4: In Patients With Be Undergoing Endoscopy For Surmentioning

confidence: 99%

ASGE guideline on screening and surveillance of Barrett’s esophagus

Qumseya¹,

Sultan

Bain

et al. 2019

Gastrointestinal Endoscopy

314

204

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Section: Question 4: In Patients With Be Undergoing Endoscopy For Surmentioning

confidence: 99%

ASGE guideline on screening and surveillance of Barrett’s esophagus

Qumseya¹,

Sultan

Bain

et al. 2019

Gastrointestinal Endoscopy

314

204

View full text Add to dashboard Cite

Utility of wide-area transepithelial sampling with 3-dimensional computer-assisted analysis as an adjunct to forceps biopsy sampling in the surveillance of patients with Barrett’s esophagus after endoscopic eradication therapy

Corbett¹,

Odze²,

McKinley³

2022

iGIE

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Wide-area transepithelial sampling in adjunct to forceps biopsy increases the absolute detection rates of Barrett’s oesophagus and oesophageal dysplasia: a meta-analysis and systematic review

Kumar

Harne

Patthipati

et al. 2020

BMJ Open Gastroenterol

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BackgroundWide-area transepithelial sampling (WATS) is a new technique that uses an abrasive brush to obtain samples from a larger surface area of the oesophagus. Studies have shown promising results that WATS in adjunct to forceps biopsy (FB) increases the detection rate of Barrett’s oesophagus (BE) as well as oesophageal dysplasia (ED). We conducted a systematic review and meta-analysis to compare the detection rates of BE and ED between FB and WATS in adjunct to FB.MethodsA Literature search was done using electronic databases, including PubMed, Embase, Scopus, Cochrane and CINAHL from inception to 26 April 2020. A meta-analysis comparing detection rates of WATS in adjunct to FB versus FB using the random-effects model was done using RevMan V.5.3.ResultsPooled data from 20 392 endoscopies across 11 studies showed an absolute increase in detection of 16% (95% CI 0.10% to 0.22%, p<0.00001). A relative increase of 1.62 was seen in detection rates of BE (95% CI 1.28 to 2.05, p<0.0001) when WATS was used with FB with the number needed to test (NNT) of 6.1 patients. For ED, a 2% absolute increase (95% CI 0.01 to 0.03, p=0.001) in additional diagnostic yield from WATS. A relative increase of 2.05 was seen in the detection rate of ED (95% CI 1.42 to 2.98, p=0.0001) yielding an NNT of 50 patients.ConclusionOur study shows that WATS, as an adjunct to FB, improves both the absolute detection rate and relative detection rate of both BE and ED as compared to FB alone.

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345 Transepithelial Brush Biopsy With Computer-Assisted Tissue Analysis Increases Detection of Residual or Recurrent Intestinal Metaplasia and Dysplasia Following Endoscopic Ablation of Barrett's Esophagus

Cited by 3 publications

References 0 publications

ASGE guideline on screening and surveillance of Barrett’s esophagus

ASGE guideline on screening and surveillance of Barrett’s esophagus

Utility of wide-area transepithelial sampling with 3-dimensional computer-assisted analysis as an adjunct to forceps biopsy sampling in the surveillance of patients with Barrett’s esophagus after endoscopic eradication therapy

Wide-area transepithelial sampling in adjunct to forceps biopsy increases the absolute detection rates of Barrett’s oesophagus and oesophageal dysplasia: a meta-analysis and systematic review

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