3D printed biocompatible polylactide-hydroxyapatite based material for bone implants

Petrovskaya, T. S.; Toropkov, Nikita; Mironov, Evgeny G.; Azarmi, Fardad

doi:10.1080/10426914.2018.1476764

Cited by 42 publications

(12 citation statements)

References 23 publications

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“…The choice of material and production process are primarily linked to mechanical, thermal and electrical requirement of the purpose of MID application. Thermoplastics materials are the most used to fabricate the MID substrate [ 63 , 64 , 65 ]. They can be subdivided on the basis of heat distortion resistance, long-term service temperature and the price of raw material.…”

Section: Thermoplastics For Midmentioning

confidence: 99%

3D-MID Technology for Surface Modification of Polymer-Based Composites: A Comprehensive Review

et al. 2020

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The three-dimensional molded interconnected device (3D-MID) has received considerable attention because of the growing demand for greater functionality and miniaturization of electronic parts. Polymer based composite are the primary choice to be used as substrate. These materials enable flexibility in production from macro to micro-MID products, high fracture toughness when subjected to mechanical loading, and they are lightweight. This survey proposes a detailed review of different types of 3D-MID modules, also presents the requirement criteria for manufacture a polymer substrate and the main surface modification techniques used to enhance the polymer substrate. The findings presented here allow to fundamentally understand the concept of 3D-MID, which can be used to manufacture a novel polymer composite substrate.

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Section: Thermoplastics For Midmentioning

confidence: 99%

3D-MID Technology for Surface Modification of Polymer-Based Composites: A Comprehensive Review

et al. 2020

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“…Данная работа является продолжением исследования взаимосвязи состава и свойств композиций КФ(ГАП)/PLA, пригодных для 3D печати путем послойного нанесения расплава материала [1]. Целью работы является изучение поведения композиций КФ(ГАП)/PLA с содержанием минеральной фазы от 5 до 45 масс % в температурном диапазоне от 25 до 300 о С, включающем диапазон 3D печати, а также определение эффективной концентрации добавки глицерина.…”

Section: томский политехнический университет томскunclassified

ISSLEDOVANIE KOMPOZITsIY PLA I FOSFATA KAL''TsIYa PRI NAGREVANII

2020

Mezhdunarodnaya Konferentsiya "Fizicheskaya Mezomekhanika. Materialy S Mnogourovnevoy Ierarkhicheski Organizovannoy Strukturoy

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“…[57] Since then, aliphatic polyesters (PHAs) have been employed in the design of artificial skins, [58] dental implants [59] and pins for internal bone fractures. [60] ROP of larger cyclic ketones such as of δ-valerolactone and allyl-δ-valerolactone provide additional properties such as flexibility and elasticity making it suitable for implantable drug delivery systems. [61] Poly-εcaprolactone (PCL) from the ROP of ε-caprolactone (ε-CL) is used as a biocompatible material in tissue engineering and surgical sutures.…”

Section: Chiral Lactones As Bio-based Monomersmentioning

confidence: 99%

Chemo-enzymatic routes towards the synthesis of bio-based monomers and polymers

Ahmed

Leferink

Scrutton

2019

Molecular Catalysis

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Scheme 7. Kinetic resolution of aromatic mandelic acid derivatives. Enantioselective hydrolysis of α-hydroxynitriles using nitrilases offer a facile approach to chiral hydroxy acids with theoretical yields of 100% in a dynamic kinetic resolution (DKR) process. Robertson et. al. identified 137 nitrilases after screening 651 environmental samples of which 44 were found to be (R) and 4 were (S)-selective on mandelonitrile. [36] Further investigation revealed nitrilase I and II to be proficient in the DKR of arylnitriles (rac-14 and 15) towards the synthesis of a panel of mandelic acid (R)-14 and phenyllactic acid derivatives (S)-15.[37] Scheme 8.Chemo-enzymatic DKR of α-hydroxynitriles towards the production of aromatic hydroxy acids. Dehydrogenases provide an alternative route to hydroxy acids via the asymmetric reduction of the pro-chiral ketone in α-keto esters. Fusion proteins consisting of glutathione Stransferase N-terminally linked to putative dehydrogenases from S. cerevisiae (Ypr1p and Gre1p) were used to reduce ethyl 2-oxo-4-phenylbutanoate to the corresponding alcohol with high enaniopurity.[38] Further systematic investigation by the same group on 18 reductases fused with GST showed activity towards α-and β-keto esters. [39] Five enzymes encoded from the yeast gene YDLI24w, YAL060w, YGL157w, YDR541c and YGL151w displayed excellent enantioselectivity across all three α-keto esters, affording the corresponding alcohol in >99% ee. Xu and co-workers engineered a highly stereoselective D-lactate dehydrogenase (D-LDH) towards a panel of aliphatic and aromatic αketoesters.[40] The Y52L mutant of D-LDH showed enhanced activity compared to the wildtype across the whole substrate panel (scheme 9). Scheme 9. Panel of α-keto acids using engineered D-lactate dehydrogenase (D-LDH). Values in brackets show % change in specific activity between wt and Y52L mutant.

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3D printed biocompatible polylactide-hydroxyapatite based material for bone implants

Cited by 42 publications

References 23 publications

3D-MID Technology for Surface Modification of Polymer-Based Composites: A Comprehensive Review

3D-MID Technology for Surface Modification of Polymer-Based Composites: A Comprehensive Review

ISSLEDOVANIE KOMPOZITsIY PLA I FOSFATA KAL''TsIYa PRI NAGREVANII

Chemo-enzymatic routes towards the synthesis of bio-based monomers and polymers

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