3d Printing: A Review on the Transformation of Additive Manufacturing

Abstract

3D printing and nanotechnology have been two of the most important tools in the development of personalized medical treatments. More recently, their alliance has developed in an effort to create new, flexible, multidisciplinary, and/or medical and drug-wise products. Therefore, a comprehensive review of scientific studies, including 3D printing and nanomaterials on the development of new pharmaceutical methods and medical applications for the treatment and prevention of diseases, is presented here with the help of secondary research from most recent articles. 3D printing, also known as additive manufacturing, has held the power of building a new class of active nanocomposites. With the ability to print a layer of complex 3D objects by layer, additional production of nanomaterials can be used in new ways to significantly control architectural structures of all sizes. The high efficiency of embedded nanomaterials can further extend the power of nanocomposites to structures such as gradients in thermal conductivity, converted photonic emissions, and increased energy and reduced weight. According to the survey done by annual industry, around 50% of the market of 3d printing in the industrial sectors is credited to created prototypes by means of photopolymers. While, Formlabs, Stratasys, HP, Desktop Metal, Ultimaker, Carbon, EOS, Nanoscribe and Markforged are among the top additive manufacturers. This work is hereby an effort to focus on different techniques, merits and demerits, applications, recent advances, relation with nanotechnology along with future aspects.

Recent Advances in the Production of Pharmaceuticals Using Selective Laser Sintering

“…This would be performed after the complete part has been sintered. By using a sacrificial binder, one is able to broaden the variety of materials that may be laser-sintered [ 57 , 58 , 59 , 60 ]. However, as compared to other methods of rapid prototyping, the range of materials (powders) that may be laser sintered without the need for a sacrificial binder is very extensive [ 61 , 62 , 63 ].…”

Role of Pharma Digitalization in Healthcare Developments

“…Consider a clinical study where the properties of live things are so accurately replicated that they can be completed in less time and with less expense while still producing great results. The "silico trial" is the name of this technique [73]. A medicine product, gadget, or intervention may be developed using it as a kind of individualized computer simulation for regulatory evaluation.…”

Topology Optimization of Gripping Jaws of Industrial Robot

“…The input geometry of the objects consists of a 3D model in STL format which is often created from a meshed 3D model. [8,9] Additive technologies allow for unique flexibility in the production and design of components with complex geometries. [9,10,12] Using a 3D method such as selective laser melting (SLS) it is possible to print metal components that are complex [13], functional, lightweight and with even higher mechanical properties compared to their forged counterparts [14].…”

“…[8,9] Additive technologies allow for unique flexibility in the production and design of components with complex geometries. [9,10,12] Using a 3D method such as selective laser melting (SLS) it is possible to print metal components that are complex [13], functional, lightweight and with even higher mechanical properties compared to their forged counterparts [14]. Due to the aforementioned benefits SLS technology has also found use in industry.…”

“…[10][11][12][13][14] The material spectrum of the products includes ceramics, metals and plastics. [9,114] The method of selective laser sintering or laser melting can be used with any powder substance. However, the material used must first be melted and then solidified by laser light after cooling.…”