3d Printing for the Future of Pharmaceuticals Dosages Forms

Abstract

With the rapid pace of development in industrial sector, the pharma sector and researchers involved are equally contributing in developing the latest technology for the growth and development. The computer-aided designs and manufacturing that provides 3 Dimensional printed dosage forms is the new step being taken into consideration. With the FDA approval to first 3D printed tablet in August 2015, Spritam, 3 Dimensional printing (3DP) has become the all new method for preparation of drug delivery system. 3D printing has the capability of dispensing the drug more accurately, precisely, and the layer by layer assembly helps in forming complex composition and geometries. 3D printing enables the preparation of personalised dosage form and tailored release profiles. 3D printing can be seen as future of solid dosage forms produced on demand, with customised dose and possibly lower in cost. It can help in reducing side effects caused by excessive doses. This review highlights the 3D printing technology and its applications in growth of pharmaceutical sector. An overview of reviews was conducted to locate published literature between 2000 and 2017.

3d Printing Technique: A Review on the Applications in Pharmaceutical Manufacturing

“…A layer-by-layer procedure called 3D printing may create 3D medicinal items from digital files. The 3D printing technology is unmatched in its flexibility, speed, and ability to manufacture pharmaceutical items of the necessary quality [9].…”

“…To meet a variety of clinical needs, precise control of drug release, a high degree of flexibility and creativity to customise pharmaceuticals, and a significant reduction in preparation development time, 3D printing offers advantages over conventional preparation technologies. These advantages include flexibility in the design of complex 3D structures within drugs, the adjustment of drug doses and combinations, and rapid manufacturing and prototyping [7][8][9]. Several pharmaceutical items, including immediate-release tablets, controlled-release tablets, dispersible films, microneedles, implants, and transdermal patches, have been manufactured using three-dimensional printing technology [10].…”

Role of Pharma Digitalization in Healthcare Developments

“…The pharmaceutical industry's supply chain operations will probably undergo a full transformation when this manufacturing technique obtains widespread. Hospitals and pharmacies might be able to print the pharmaceuticals they need on-site in ten years [71].…”