3D super-resolution MR elastography of the brain

Abstract

MR elastography (MRE) provides valuable quantitative information about the mechanical properties of brain tissues. However, due to SNR limitations, often only low through-plane resolution is possible. We present super-resolution MRE based on multiple stacks of complex 3D wavefields of the brain resulting in elastograms with isotropic (1×1×1) mm3 resolution. The approach was evaluated for the in-vivo brain and showed improved visibility of fine structures while presenting consistent shear wave speed values.