This paper is centered on applying 3D omnidirectional scanning technology to design natural textured fabrics to explore its functionality in psychological healing. The therapeutic potential of fabric art has been widely recognized due to the prevalence of psychological stress in modern society. This study uses 3D omnidirectional scanning technology to scan knitted textures, optimize fabric texture models, and conduct experimental research and material development using elevation and lighting angles. The size, Angle, color, and other factors that affect the experiment of knitted materials were tested, and eight convenient materials were selected for psychological experiments. A two-week experiment was conducted to record and analyze changes in the psychological state of 30 subjects (15 men and 15 women). It was obtained that the intervention group using simulated fabrics decreased from an average of 38.14 to 27.25 in the level of mental awareness, which was significantly higher than the control group (p<0.01). In terms of mental health indicators, the intervention group showed significant improvement in depression, anxiety, and other dimensions. Using 3D omnidirectional scanning technology to simulate natural texture fabric design positively enhances mental awareness and improves mental health, which has a promising potential for psychological healing.