2011
DOI: 10.1016/j.humimm.2011.07.292
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47-OR: HLA DQ antibodies are the most frequent antibodies encountered in antibody-mediated rejection (AMR) of renal allografts

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“…The significance of the DQ antibodies is increasingly recognized following the introduction of the SAB assay which considered today to be the most sensitive and specific method for alloimmunization assessment [13][14][15]. However, it is becoming clear that the detection of the HLA antibodies by SAB is not absolutely perfect due to the variation in densities and orientations of the antigen coated beads [16][17][18].…”
Section: Discussionmentioning
confidence: 99%
“…The significance of the DQ antibodies is increasingly recognized following the introduction of the SAB assay which considered today to be the most sensitive and specific method for alloimmunization assessment [13][14][15]. However, it is becoming clear that the detection of the HLA antibodies by SAB is not absolutely perfect due to the variation in densities and orientations of the antigen coated beads [16][17][18].…”
Section: Discussionmentioning
confidence: 99%