495 Maternal and Endogenous Iga Protection in Infants with Respiratory Tract Infections

Abstract

Goal Study of spreading of bronchial asthma (BA) and risk factors in the climate of the region of Georgia in children's populations of Tbilisi and Batumi. Materials and methods Study included 4559 children of Tbilisi and Batumi of 5-16 age, 2193 girls, 2366 boys. Children's population was selected by cluster method. At the first stage identification of BA symptoms was provided based on the questionnaire. At the second stage clinical-allergological study of 389 children with positive answers took place. Obtained data were processed by means of SPSS/v12.5 software. Evaluation of degree of association between probability of disease and certain risk-factor was provided based on tetrachoric table (2x2). Obtained results BA symptoms were analysed, distribution frequency by sex, set of diagnostic criteria was reliably high (p=0.002) among boys. Obtained results showed that in Batumi BA diagnosis was made in 6.4% of cases and on Tbilisi-in 4.6% of cases. Clinical-allergological study showed that among children with BA number of boys exceeded girls (p<0.01). BA factors included: humidity (76.4%), weather (56.9%), cloudy and rainy weather (44.3%), season (24.6%), tobacco smell (29.8%), respiratory infections (34.2%), dust (28.5%), physical load (19.7), medicament sensibilization (11.2%) etc. Conclusion Epidemiological study showed high BA frequency in Batumi (6.4%), compared with Tbilisi children's population (4.6%). Identification of risk factors provides basis for development of prevention programs. Data of BA spreading obtained by this study are dramatically different from official data (0.4%) showing high frequency of hipodiagnostiscs of bronchial asthma in region (p<0.01).