4CPS-150 Evaluation of intra-patient variability of the tacrolimus plasmatic levels in different periods after liver transplant

Abstract

Conclusion FKplasm and IPV during induction are higher than in EM and LM. However, patients with CV >30% remain in the maintenance periods between 29.9% and 31.8%, and with values<5 ng/ml between 9.3% and 13.1% which would justify a greater need for pharmacokinetic monitoring and therapeutic control, in order to preserve a longer graft survival and to minimise the events of pharmacological adverse reactions.